COMPARATIVE EFFECTIVENESS OF APPLICATION OF ACETYLCYSTEIN IN PERORAL AND INHALATION FORM FOR NEBULIZER THERAPY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Journal Title: Астма и Аллергия - Year 2019, Vol 1, Issue 1
Abstract
Purpose of the study: to research the dynamics of the sensitization structure in children with bronchial asthma, living in Lviv, in during 5 years (2012-2016 years) and to analyze its age characteristics. Materials and methods: a retrospective analysis of outpatient cards and medical files of 904 children with bronchial asthma, aged 6–18 years, from 2012 to 2016, living in Lviv, has been conducted. The sensitization profile was assessed by the results of skin allergic tests (prick and scarification tests) using Ukrainian ("Immunologist"), and foreign ("Diater," Spain and "Sevafarma," Czech Republic)allergen manufacturers. The children were divided into three age groups: 6-8, 9-14 and 15-18 years old. Among the surveyed children, the number proportion of boys was 62 %, girls - 38 %. Results: in the sensitization structure of children, house dust allergy prevailed in all age groups (662 children - 73.3 %), mainly, the sensitization to the dust mites allergen - Dermatophagoides pteronyssinus was detected in 94.1 % of children to with house dust sensitization. The second most common reason of sensitization were was epidermal allergens (52.1 % - 471 children). Less commonly diagnosed was fungal (34.18% — 309 patients), pollen (26.77 % - 242 patients) and food (19.91 % - 180 patients) sensitization. Conclusions: The retrospective analysis (during 2012-2016) of the results of allergen testing children with bronchial asthma, living in Lviv, showed that household allergy predominates (p < 0,05) in the sensitization structure (73.32 %), in particular, sensitization to house allergens of house dust mites Dermatophagoides pteronyssinus. The obtained results allow to confirm literary data regarding the primary source of house dust allergens - mites.
Authors and Affiliations
L. Besh, Z. Slyuzar
Keywords
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- EP ID EP543301
- DOI 10.31655/2307-3373-2019-1-22-26
- Views 107
- Downloads 0
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