Comparative evaluation of antimicrobial efficacy of two intracanal medicaments and irrigants in conjunction to each other: An in vivo study
Journal Title: Medpulse International Journal of Dentistry - Year 2018, Vol 6, Issue 1
Abstract
Background: Due to the complex anatomy of the root canal, mechanical instrumentation leaves significant portions of the root canal walls untouched and there is no evidence that instrumentation alone can completely eliminate microorganisms from the root canal. Therefore additional irrigants and medicaments are required to disinfect the root canal system to reduce the bacterial load to promote healing. Aim: This study aims to evaluate and compare the antimicrobial efficacy of calcium hydroxide and triple antibiotic paste(metronidazole, ciprofloxacin and cefaclor) as intra-canal medicaments in presence of different irrigants as, chlorhexidine and sodium hypochloride, by microbial quantification. Materials and Methods: The present study is randomized controlled trial which aims to assess the antimicrobial efficacy of calcium hydroxide and triple antibiotic paste(metronidazole, ciprofloxacin and cefaclor) as intra-canal medicaments in presence of different irrigants as, chlorhexidine and sodium hypochloride. In the present study all the subjects visiting to the department of Pedodontics will be included after obtaining voluntary informed consent from the subjects’ parents/guardians. Results: All the groups in the study, i.e: group IA, IB, IIA, and IIB showed reduction in the pre- and post-operative microbial count present in the root canals. Whereas among all the groups, the group IIA tend to show the most reduced microbial count, followed by IIB, IA and IB respectively. Conclusion: Adequate amount of irrigation and an appropriate intra-canal medicament can help in achieving this goal. Use of irrigants and intra-canal medications in conjunction with each other will give a synergistic effect in the disinfection protocol.
Authors and Affiliations
Sachin A Gunda, Priyanka A Jare, Ankita Hingmire, Anil Patil, Sandhyarani Hudar, Sridevi Tamagond
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