COMPARATIVE EVALUATION OF CLINICAL AND MICROBIOLOGICAL EFFICACY OF 2% LEMONGRASS GEL VERSUS 1%CHLORHEXIDINE GEL AS A LOCAL DRUG DELIVERY SYSTEM IN THE TREATMENT OF CHRONIC PERIODONTITIS: A RANDOMIZED CONTROLLED CLINICAL TRIAL.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 7
Abstract
Background: research has revealed various medicinal plants offering new choice of antimicrobial therapy. Cymbopogon citratus (lemongrass) is a popular medicinal plant, at concentration of ≤ 2%; it inhibits several microorganisms including periodontal pathogens. Aim: to compare and evaluate, clinically and microbiologically, the efficacy of 2% lemongrass gel versus 1% chlorhexidine gel as a local drug delivery agent in patients with chronic periodontitis after mechanical periodontal therapy. Materials and methods: 45 systemically healthy patients with chronic periodontitis were included in the study. All the patients underwent scaling and root planing (SRP), patients were recalled after 1 month.Those having persistent probing pocket depth ≥ 5mm were selected for the study and were equally divided into 3 groups of 15 patients each. Group I received lemongrass gel, group II received chlorhexidine (CHX) gel and group III received placebo gel as a local drug delivery agent. Clinical parameters like gingival index (GI), plaque index (PI) and probing pocket depth (PPD), clinical attachment level (CAL) were evaluated at baseline and 3 months follow-up. Microbial analysis was done by using subgingival plaque samples before and after treatment. Results: when lemongrass results compared with chx gel, the results were statistically insignificant (p>0.05) and when compared with placebo result where significant. Conclusion: the LDD containing 2% lemongrass gel can be effectively used in the treatment of chronic periodontal pockets and is as effective as CHX gel in the treatment of chronic periodontitis.
Authors and Affiliations
Kunal S. Sethi, Aishwarya M. Kale, Swapna A. Mahale
Keywords
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- EP ID EP365707
- DOI 10.21474/IJAR01/7373
- Views 74
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