COMPARATIVE EVALUATION OF CLINICAL EFFICIENCY AND COST-EFFECTIVENESS OF TARGETED CANCER THERAPY

Abstract

The high prices of the targeted TKI therapies cause fierce debates in Bulgaria and in economically developed countries. All questions about the cost-effectiveness of TKI therapies motivate a number of researchers to examine the ratio of costs and benefits. However, no comprehensive analysis is available to provide updated information about the cost-effectiveness of all TKI therapies and objectify the decision-making process on reimbursement in Bulgaria. Our team implemented a comprehensive analysis of published international data on cost-effectiveness of oral targeted cancer therapies based on tyrosine kinase inhibitors. The purpose of the analysis is to support the decisions of the NCPRMP in Bulgaria to include TKI therapies in the PdL and set the starting point for adapting and updating of pharmacoeconomic evaluations.

Authors and Affiliations

Toni Vekov, Petko Salchev, Nadya Veleva, Evgeni Grigorov, Hristina Lebanova

Keywords

Related Articles

SPECIFIC CHARACTERISTICS OF HUMAN RESOURCES IN HEALTHCARE

Nowadays, the theme of human resources in healthcare system is of vital importance. In health sector there are several groups of resources - material, technical, information, financial, time, and natural, and others. But...

TRENDS IN THE INTERNET USE FOR HEALTH-RELATED INFORMATION AMONG THE BULGARIAN POPULATION AGED 20 AND OVER

Globally there has been a steady increase in consumers seeking health information on the Internet. A good knowledge of Internet audiences is an important factor in the effective use of this health communication channel....

MONTHS OF THE YEAR AND DOMESTIC VIOLENCE

Domestic violence is among the topical and signifi cant social problems of the modern age. While the issue has been discussed in Western Europe and the United States for a long time, in Bulgaria it has long been passed o...

EFFECT OF THE FAMILY ENVIRONMENT ON THE INTERNAL MOTIVATION OF SERVICEMEN IN BULGARIA

This paper presents material that explores the psychodynamics of intra-familial factors that directly affect the ability of officers to deal with the requirements of the military environment, as well as their internal mo...

SITUATION ANALYSIS OF MUNICIPAL MULTIPROFILE HOSPITALS FOR ACTIVE TREATMENT (MHAT). OPERATIONAL PROBLEMS AND REASONS FOR CLOSURE

Impatient care establishments are commercial entities and as such can be the subject of any known type of corporate assessment. On the other hand, hospitals operate in a quasi-market. This fact makes it difficult to appl...

Download PDF file
  • EP ID EP475574
  • DOI -
  • Views 63
  • Downloads 0

How To Cite

Toni Vekov, Petko Salchev, Nadya Veleva, Evgeni Grigorov, Hristina Lebanova (2015). COMPARATIVE EVALUATION OF CLINICAL EFFICIENCY AND COST-EFFECTIVENESS OF TARGETED CANCER THERAPY. Българско списание за обществено здраве (Bulgarian Journal of Public Health), 0(1), 22-63. https://europub.co.uk/articles/-A-475574