Comparative evaluation of controllability and safety of therapeutic hypothermia in the intensive care of severe traumatic brain injury
Journal Title: Медичні перспективи - Year 2017, Vol 22, Issue 4
Abstract
The article presents the results of a comparative study of control and safety of two technologies of therapeutic hypothermia in intensive care in patients with TBI: an estimate of the rate of its induction, control of its maintenance, dynamics of attaining normothermia. A total of 24 patients with a severe TBI divided into 2 groups were examined: I (n=12) – therapeutic hypothermia with "Blanketrol II" (CSZ) with the use of non-invasive technology to achieve the target core body temperature (Tco) of 34-34.50C; II group (n=12) – carrying out therapeutic hypothermia «Blanketrol - II» with the use of an esophageal device for hypothermia to achieve Tco - 34-34,50С. The mean time from the moment of induction to achievement of the target Tco in group I was 9.5±2.39 hours, in group II – 9±2.70 hours (p>0.05). The maintenance period Tco at the level of ≤34.50C in the II group was greater – 10.5±5.78 compared with 6.83±3.95 hours in patients of the I group (p<0.05). Control of the warming process was significantly higher in group II, which was reflected by a lower mean of Tco value at 24, 28 and 32 hours. There were no clinically significant adverse effects in therapeutic hypothermia.
Authors and Affiliations
A. V. Tsarev, L. V. Usenko
Dynamics of cytokines level under the influence of lyophilized dialysate of leucocytes (Immodin) on the background of allergen-specific immunotherapy (ASIT) by pollene allergens in patients with pollinosis
The analysis of IL-4, INF-γ has been performed on the background of lyophilized dialysate of leucocytes (Immodin) in the course of the ASIT with pollen allergens among patients with pollinosis. 104 people of both gend...
Гемодинаміка, функціональний стан ендотелію судин, нирок та тромбоцитів залежно від індексу маси тіла при хронічній серцевій недостатності зі збереженою систолічною функцією
Целью работы было оценить состояние гемодинамики, функции эндотелия, почек и тромбоцитов у больных с хронической сердечной недостаточностью (ХСН) с сохраненной систоли¬ческой функцией в зависимости от индекса массы тела...
Механізми гематогенного метастазування пухлин
Метастазирование является самой распространенной причиной смертности, ассоциированной с раком, тем не менее, наше понимание этих процессов остается недостаточным. Метастазирование - это конечный продукт динамического пр...
Фітотерапевтичні лікарські засоби з нефропротекторною активністю (огляд)
Фитотерапевтические лекарственные средства с нефропротекторной активностью (обзор). Подплетняя Е.А., Хомяк Н.В., Соколова Е.В., Кайдаш С.П., Хомяк Е.В. В статье проанализированы особенности химического состава и фармакод...
Risk factors and prediction of inflammatory complications and local secondary osteoporosis in the bone structure of jaws in dental intraosseous implantation in healthy subjects
As a result of complex clinical, immunologic and biochemical investigations of 48 patients peculiarities of development of inflammatory complications, local osteoporosis and destruction of bone tissue after performed den...