Comparative evaluation of different doses of PPAR-γ agonist alone and in combination with sulfasalazine in experimentally induced inflammatory bowel disease in rats.
Journal Title: Pharmacological Reports - Year 2013, Vol 65, Issue 4
Abstract
Inflammatory bowel disease (IBD) is an idiopathic, chronic inflammatory condition, which affects the gastrointestinal tract and has no curative treatment. The present study aimed to investigate the effect of different doses of pioglitazone alone and in combination with sulfasalazine in TNBS (trinitrobenzenesulfonic acid)-induced inflammatory bowel disease (IBD) in rats.
Authors and Affiliations
Prasad Byrav D. S. , Bikash Medhi, Ajay Prakash, Amitava Chakrabarti, Kim Vaiphei, Krishan Khanduja
Keywords
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