Comparative Evaluation of Efficacy of Dexmedetomidine and Propofol for Sedation in Patients Undergoing Gastrointestinal Endoscopy
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 10
Abstract
Background: Gastrointestinal Endoscopy is performed as diagnostic and therapeutic procedure. Data from a recent meta-analysis suggest that propofol sedation is not associated with an increased risk of complications. Dexmedetomidine can be safely used as a sedoanalgesic agent in colonoscopies because it provides efficient haemodynamic stability, higher satisfaction scores and lower Numeric Rating Scale scores. Under the light of above mentioned data, we planned the present study to compare the efficacy of propofol and dexmedetomidine in patients undergoing gastrointestinal endoscopy. Materials & methods: The present study included comparison of efficacy of propofol and dexmedetomidine in patients undergoing gastrointestinal endoscopy. A total of 40 patients scheduled to undergo gastrointestinal endoscopy were included in the present study and were broadly divided into two study groups: Group I: 20 Patients receiving propofol, Group II: 20 Patients receiving dexmedetomidine. Modified aldrete score (MAS) was calculated based on the criteria described previously in the literature.8- 10 All the results were analyzed by SPSS software. Results: Mean time to MAS was significantly higher for the propofol group (451.5 seconds) in comparison to the dexmedetomidine group (140.8 seconds). Mean PSS (Patient Satisfaction Score) of subjects of propofol group and dexmedetomidine group was found to be 41 and 43 respectively. However; the difference was found to be statistically non-significant. Conclusion: Although both the analgesic agents were statistically equally effective, efficacy of dexmedetomidine might be more in patients undergoing endoscopy.
Authors and Affiliations
Anil Bhati
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