COMPARATIVE EVALUATION OF EXTRACTS OF SENNA UNIFLORA FOR ANTI-INFLAMMATORY ACTIVITY
Journal Title: International Journal of Pharmacy and Technology - Year 2010, Vol 2, Issue 2
Abstract
Aims and Objective: To study the benzene, alcohol and petroleum ether extract of Senna uniflora treatment against carrageenan induced paw oedema in albino rat model. Methods: The benzene, alcohol and petroleum ether extracts of Senna uniflora was given to paw oedema induced albino rats at doses administered intraperitoneally (I.P.) ranged from 50 to 200 mg/kg body weight, which comparable with indomethacin (10 mg/kg) used as a reference drug. Results: The benzene and alcohol extracts administrated orally at dose of 200 mg/kg produced significant (P < 0.05) oedema inhibition when compared with indomethacin. Conclusion: The result suggested that benzene and alcohol extracts of Senna uniflora, showed significant inhibition on paw oedema albino rats. This study reveals the possible rationale for its folkloric use as an anti-inflammatory agent.
Authors and Affiliations
Abdul Ali Ahmed
Keywords
Related Articles
- EP ID EP91782
- DOI -
- Views 159
- Downloads 0
ASSAM BORA RICE STARCH AS DIRECTLY COMPRESSIBLE FILLERBINDER
Introduction: North-east India, including Assam, is recognized as a centre of origin of rice and is endowed with exceptionally rich rice diversity. Assam Bora rice (Oryza sativa L, Japonica variety), a group of glutinous...
A REVIEW OF p38 KINASE INHIBITORS AS ANTI-INFLAMMATORY DRUG TARGETS
The p38 protein kinase is a serine-threonine mitogen activated protein kinase, which plays an important role in inflammation and arthritis. p38 subgroup of the mitogen activated protein kinase super family has four isofo...
VALIDATION OF REVERSED - PHASE HPLC METHOD FOR THE ESTIMATION OF CEFIXIME IN CEFIXIME ORAL SUSPENSION.
A simple, fast, precise and accurate, high performance liquid chromatographic method for estimation of Cefixime in Cefixime Oral Suspension was validated using C18 [Hypersil ODS], 4.6x250mm, 5 microns with mobile phase c...
SYNTHESIS OF NEW RING SYSTEM 6,7,8,9 TETRA HYDRO-5H-5-(2'- HYDROXY PHENYL)-2-(4'-SOME SUBSTITUTED BENZYLIDINE)-3-(4- NITROPHENYL AMINO) THIAZOLO QUINAZOLINE
A convenient synthesis of the 6,7,8,9 tetra hydro-5H-5-(2'-hydroxy phenyl)-2-(4'-some substituted benzylidine)-3-(4-nitrophenyl amino) thiazolo quinazoline ring system is reported. Our synthetic approach consisted of the...
IMMUNOHISTOCHEMICAL DETECTION OF ESTROGEN AND PROGESTERONE RECEPTORS OF HER-2/NEU RECEPTOR IN HUMAN MAMMARY CARCINOMA
The present study was designed to evaluate the expression of estrogen and progesterone receptor as biomarkers in human benign and malignant mammary tumors. Tissue samples from tumors and adjacent uninvolved areas from fi...