Comparative evaluation of high sensitivity C - reactive protein (HS-CRP) in patients with healthy gingiva and chronic generalized periodontitis (CGP) without coronary artery disease (CAD)
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
Objective: The aim of the study was to compare and evaluate levels of hs-CRP in the serum samples of patients with healthy gingiva and CGP patients without CAD. Material And Method: A total of 40 systemically healthy patients were selected and divided into 2 groups- Patients with healthy gingiva (Group A) and with Chronic Generalized Periodontitis (Group B). The periodontal status was assessed and peripheral blood was collected and hs-CRP levels were estimated in the serum samples. Result: hs-CRP levels were compared and evaluated in patients with CGP and healthy gingiva. The mean hs-CRP levels in Group A recorded was 0.30 ± 0.208 and Group B was 2.25 ± 0.788. Pearson correlation was used to analyze the relationship between hs-CRP and probing pocket depth. When correlation between PD and hsCRP was evaluated then a statistically highly significant correlation was found (r = 0.976, p > 0.01). Conclusion: Patients with chronic generalized periodontitis(CGP) revealed higher levels of hs-CRP than in healthy gingiva patients and this strong association between CGP and hs-CRP revealed the susceptibility to cardiac diseases such as Myocardial infarction and Coronary Artery diseases.
Authors and Affiliations
Rishikesh Anjan Desai
Keywords
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