Comparative Evaluation of Intrathecal Administration of Isobaric Levobupivcaine (0.5%) and Isobaric Ropivacaine (0.75%) in Patients Undergoing Lower Limb Surgeries
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Bupivacaine available as a recemic mixture of its enantiomers dextro and levo bupivacaine has been the gold standard for intrathecal use in spinal anesthesia. Levo bupivacaine and Ropivacaine are the two recently introduced alternatives to Bupivacaine in clinical practice. The aim of our study is to evaluate the effect of intrathecal administration of isobaric Levobupivacaine and isobaric Ropivacaine in patients undergoing lower limb surgeries. Material and methods: Sixty patients were grouped equally in group I and II, who received intrathecal 3 milliliter (0.5%) isobaric Levo Bupivacaine (15 milligram), and 3ml (0.75%) isobaric Ropivacaine (22.5mg) respectively. Results: The observations were discussed in terms of vital parameters; onset, duration and recovery from sensory and motor blockade and side effects. It was found that isobaric Ropivacaine 0.75% intrathecally provides shorter duration of motor and sensory block compared to Levo bupivacaine 0.5%. Conclusion: Also there were less episodes of hypotension which indicate that 0.75% isobaric Ropivacaine provides more hemodynamic stability than Bupivacaine 0.5% intrathecally.
Authors and Affiliations
Rajni Thakur, Ranjita Aske, Urmila Keshari
Keywords
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