Comparative Evaluation of Intravenous Granisetron Hydrochloride and Intravenous Lignocaine Hydrochloride to Alleviate the Pain on Propofol Injection
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 1
Abstract
Propofol is one of the most commonly used induction agent. Pain on injection still remains a considerable concern for anaesthesiologist. The aim of the study was to assess the efficacy of granisetron HCL and ligocaine HCL to alleviate the pain on propofol injection. Methods: Fifty patients aged 18-50 years, ASA grade 1-2, posted for elective surgeries under general anaesthesia were randomly divided into two groups. Group G received 2 ml (1 mg/ml) granisetron while group X received 2 ml (2%) ligocaine intravenously before propofol injection. Manual venous occlusion was done for 1 minute after pre-treatment drug. 2 ml of total calculated dose of propofol was given over a period of 4 seconds. Patients were asked about the pain on injection with use of verbal rating score chart after 15 seconds. HR, SBP, DBP, SpO2 was measured 0, 1, 3 minute after propofol injection. Results: HR, SBP and DBP were significantly raised in granisetron group as compared to lidocaine group. Average pain score in group G was 2.1 while in group X it was only 0.8, which was statistically significant. (p<0.05). Conclusion: We conclude that lignocaine HCL is better than granisetron for alleviating pain after propofol induction.
Authors and Affiliations
Jenish C Patel
Keywords
Related Articles
- EP ID EP601120
- DOI 10.21088/ijaa.2349.8471.6119.37
- Views 81
- Downloads 0
Therapeutic Efficacies of Dexmedetomidine and Tramadol on Post Subarachnoid Block Shivering: A Prospective Study
Background and Aim: Shivering is a physiological response to core hypothermia in an attempt to raise the metabolic heat production. Non-pharmacological methods using equipment to maintain normal temperature of the body a...
Comparison Intraarticular Ropivacaine and Ropivacaine Plus Dexmedetomidine for Post Operative Analgesia in Arthroscopic Knee Surgery
Arthroscopic knee surgery is routinely performed these days for various indications none the less with pain in post operative period requiring analgesic cover. Pain is mediated through Opiate receptors in intraarticular...
Effect of Epidural Labour Analgesia on Maternal Body Temperature
Epidural analgesia is an effective mode of labour analgesia. Few studies have shown that epidural analgesia is associated with an increase in maternal body temperature. The greatest impact of this increase in maternal bo...
Assessment of Clinical Performance of Supraglottic Airway Devices in Adults for Short Surgical Procedures
Aim: In the present study we compared the clinical performance of the I-gel and LMA in terms of the effectiveness and safety administration in anesthetized patients. Materials & Methods: A total of 100 patients with req...
Comparison of Effectiveness of Dexmedetomidine versus Propofol during a wake Fibre-optic Naso-tracheal Intubation
Awake fibreoptic intubation (AFOI) is often the preferred method for airway management in patients with difficult intubation. The success of AFOI is highly dependent on use of various sedatives, in addition to adequate p...