Comparative Evaluation of Serum Ceruloplasmin Levels in Chronic Periodontitis Patients with and Without Diabetes Before and After Non-Surgical Periodontal Therapy
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 9
Abstract
Introduction: Periodontitis is a common local inflammatory disease of tooth supporting tissues initiated by microorganisms present in dental plaque. Ceruloplasmin is 122 K-D multi copper binding plasma protein helps in transferring of copper that converts ferrous iron into ferric form. It is an acute phase reactant seems to increase in inflammatory conditions. Aims and objectives: This study was taken up to compare and evaluate serum ceruloplasmin levels in chronic periodontitis patients with and without diabetes before and after non surgical periodontal therapy. Materials and Methods: Group A: Ten patients diagnosed with chronic periodontitis without diabetes. Received scaling and root planning with mean pocket depth of 6mm, 5ml blood was drawn at baseline and 3 months after scaling and root planning Group B: Ten patients diagnosed with chronic periodontitis with diabetes. Received scaling and root planning with mean pocket depth of 6mm, 5ml blood was drawn at baseline and 3 months after scaling and root planning. Results: Study was statistically significant in chronic periodontitis patients with diabetes than with the patients without diabetes. p value is <0.001 it is significant. Conclusion: Successful non-surgical periodontal therapy improves serum ceruloplasmin levels concentration in non diabetic patients when compared with diabetic patients.
Authors and Affiliations
Divya Kadali
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