Comparative Evaluation of the Analgesic Efficacy of Transverses Abdominis Plane Block by Using Levobupivacaine and Levobupivacaine With Magnesium Sulfate in Patients Undergoing Laparoscopic Cholecystectomy Surgery
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 3
Abstract
Abstract: Major abdominal surgeries are associated with severe postoperative pain. If untreated, it can lead to cardiac and respiratory problems thereby increasing postoperative morbidity. Our aim was to evaluate the efficacy of magnesium sulfate as an adjuvant to Levobupivacaine in an ultrasound-guided transversus abdominis plane (TAP) block for postoperative analgesia in Laparoscopic Cholecystectomy surgeries. This randomized, double-blinded clinical study included 60 patients undergoing laparoscopic Cholecystectomy surgeries. All patients were divided into 2 groups of 30 patients each. Group L received a TAP block with 20 mL per side of 0.375% levobupivacaine plus 1ml normal saline. Group M received a TAP block with 20 mL per side of 0.375% levobupivacaine plus 200mg magnesium sulphate (diluted to 1ml). Visual analog scale (VAS) scores, the duration of postoperative analgesia and any side effects were assessed and recorded. The mean postoperative VAS score was significantly reduced in group M compared to group L. The duration of postoperative analgesia was significantly prolonged in group M, compared to group L which was statistically significant. No significant difference in side effects was observed in both groups. The additions of 200 mg of magnesium sulfate to Levobupivacaine in an ultrasound-guided TAP block significantly prolonged the duration of analgesia, and reduced the VAS score in patients who underwent laparoscopic Cholecystectomy, without any significant side effects.
Authors and Affiliations
Dr. Prativa Panda, Dr. Khageswar Raut, Dr. Debasish Debata, Dr. Devishree Das, Dr. Soumyakant Mallick
Keywords
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