Comparative Evaluation of the Effect of Annona muricata (Graviola) Leaves Extracts and Cefoxitin on Staphylococcus aureus
Journal Title: Asian Journal of Biology - Year 2017, Vol 3, Issue 3
Abstract
Resistance of Staphylococcus aureus to beta- lactam drugs most especially cefoxitin is a known global problem. Current researches are geared toward evaluating the antimicrobial properties of medicinal plants against these organisms. This study was aimed at comparatively evaluating the antimicrobial effects of cefoxitin and Anonna muricata (Graviola) against Staphylococcus aureus strains. A total of ten Staphylococcus aureus strains obtained from the Microbiology Department of General Hospital were subjected to susceptibility testing against cefoxitin and Anonna muricata extracts (both aqueous and ethanol), respectively using standard microbiology techniques. Out of the 10 isolates tested, 4 (40%) showed resistance to cefoxitin, 2 (20%) were intermediate while 4 (40%) showed susceptibility. However, 8 (80%) out of 10 isolates showed susceptibility to Annona muricata ethanol extract while 2 (20%) were resistance. In addition, 9 (90%) out of the 10 isolates showed resistance to Anonna muricata aqueous extracts. This study reveals that the isolates of Staphylococcus aureus were significantly more susceptible to alcohol extract of A. muricata than to cefoxitin consistently at concentration of 500-800 mg. There is a need for further studies aimed at evaluating its potentials against other isolates.
Authors and Affiliations
U. E. George, C. I. Mboto, E. N. Mbim, U. O. Edet, C. F. Umego, H. Sunday
Keywords
Related Articles
- EP ID EP337789
- DOI 10.9734/AJOB/2017/34555
- Views 75
- Downloads 0
First Report on Zooplankton Abundance and Composition in Hadhramout Coast, Gulf of Aden
Five stations were investigated to represent the Hadhramout coast in the Gulf of Aden. This area, totally or partially, is under the influence of the western Indian Ocean seasonal monsoons. Zooplankton was collected mont...
Plants as Expression Systems for Recombinant Proteins
Plants provide a wide range of important biological molecules that are needed in research, medicine and industry. Currently, there is a growing interest in the use of plants as expression systems for the production of re...
Biological Characteristics of Indigenous Chrysoperla carnea (Neuroptera: Chrysopidae) Fed on a Natural and an Alternative Prey
Studying of prey suitability for indigenous insect predators is very important factor for their mass rearing in the future. We tested the effects of two different prey species on the preimaginal stages parameters and adu...
A Study of Acute Toxicity and Cytotoxic Activity of Prunus avium Extracts against Artemia salina Larva
Aim: This investigation was aimed at determining the cytotoxic activity of Prunus avium leaf and stem bark extracts as well as their acute toxicity in rats. Methodology: The plant materials were air dried and grinded mec...
Morphological and Molecular Evaluation of Genetic Diversity of Wild Tunisian Oregano, Origanum vulgare L. subsp. glandulosum Desf. Ietswaart
Aim: The objective of this work was the search for morphological and molecular markers useful for the analysis of genetic diversity of Origanum vulgare L. subsp. glandulosum in the northern region of Tunisia. Study Desig...