Comparative evaluation of various antibiotic therapies in diabetic patients undergoing dental surgical procedures
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 12
Abstract
Background: The effect of clindamycin prophylaxis on the prevention of bacteremia following dental procedures has been evaluated in very few studies, and the results of those studies do not confirm the efficacy of clindamycin. Moreover, increasing resistance to CLI among streptococci isolated from the bloodstream after dental extractions has been found; this could limit its use as a prophylactic drug. Aim: To compare efficacy of prophylactic Amoxicillin and Clindamycin in diabetic patients. Materials and method: The present study was conducted in the department of oral surgery of the dental institution. For the study we selected 40 diabetic patients scheduled for extraction of molars. The patients were randomly divided into two groups, Group A and B with 20 patients in each group. The patients in Group A were given Amoxycillin 500 mg prophylactically before 1 hour of anesthesia and patients in Group B were given Clindamycin 600 mg prophylactically before 1 hour of anesthesia. The scoring of pain and inflammation was done on the follow up visit from score 0 to 4. Results: A total of 40 patients were included in the study. Number of male patients was 26 and number of female patients was 24. The mean age of the subjects was 42.23 + 2.1 years ranging from 21 to 65 years. We observed that number of patients with Score 0 was 15 in Group A and 10 in Group B. Number of patients with Score 1 was 2 in Group A and 5 in Group B. Number of patients with Score 2 was 2 in Group A and 3 in Group B. Number of patients with Score 3 was 1 in Group A and 2 in Group B. Number of patients with Score 4 was 0 in both the groups. On comparing the results we observed statistically non-significant results. Conclusion: Within the limitations of the present study, we conclude that Amoxicillin and Clindamycin can be prescribed as prophylactic antibiotics for diabetic patients with positive results
Authors and Affiliations
Junaid Ashraf
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