Comparative Fatty Acids Profiling and Antioxidant Potential of Pawpaw and Watermelon Seed Oils
Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 14, Issue 4
Abstract
Seed oils of watermelon, unripe and ripe pawpaw were extracted and analyzed for their fatty acid composition using GC/EIMS, phenolic content and antioxidant potential using free radical scavenging effect on 2, 2-diphenyl-2-picrylhydrazyl (DPPH) radical. Watermelon seed oil has eight fatty acids ranging from C16 – C21, unripe pawpaw seed oil has nine fatty acids also ranging from C16 – C21 and ripe pawpaw seed oil has twelve fatty acids ranging from C15-C27. The major chemical component identified in both watermelon seed oil (49.41%) and unripe pawpaw seed oils (39.07%) was 11-Octadecenoic acid methyl ester while 14-Octadecenoic acid methyl ester (40.25%) was the major component identified in ripe pawpaw seed oil. Only watermelon seed oil contained an essential fatty acid; linoleic acid (17.23%) in contrast to previous literatures values (60%). The fatty acids present in these oils are mixtures of saturated and unsaturated homologues. Ripe pawpaw seed oil showed more chemical compounds than the unripe pawpaw seed oil and this may be due to ripening. The phenolic contents of the oils ranged from 1.41-1.55 mg gallic acid equivalent per gram. The three oils showed significant DDPH free radical scavenging potential. The order of inhibition are; watermelon > ripe pawpaw > unripe pawpaw seed oil. The IC50 values of these oils were are, 36 mg/ml, 44 mg/ml and 56 mg/ml for watermelon, ripe pawpaw and unripe pawpaw seed oils respectively. This study however did not show a positive correlation between the phenolic contents and antioxidant activity. We recommend further studies into the use of these oils for treating various specific diseases.
Authors and Affiliations
Banji Adaramola, Onigbinde Adebayo
Keywords
Related Articles
- EP ID EP342276
- DOI 10.9734/BJPR/2016/27974
- Views 90
- Downloads 0
Cell-specific Reduction in Viability of Two Breast Cancer Cell Lines after Exposure to Gold Nanoparticles
Aims: Nanoparticle composites are a recent research hotspot, with the potential to be drug-delivery vehicles for more efficient treatment of malignant cancerous tumors. However, as this is a relatively new field, the saf...
In vitro Cytotoxicity of Scopoletin Derived from Eupatorium laevigatum Lam.
Aims: Eupatorium laevigatum Lam. is commonly used as anti-inflammatory, antiseptic, anti-rheumatic, and in the treatment of colds and ulcers. The present study aimed to characterize the active fractions of the aerial par...
In vitro Proliferation and Wound Healing Effects of Narcissus tazetta L. Bulb on Primary Human Dermal Fibroblasts
Aims: Narcissus tazetta L. bulbs have been used in Traditional Persian medicine (TPM), as "Zaroor" for wound healing. Toward quality assurance of the plant, pharmacognostic and phytochemical studies, physicochemical char...
Effects of Ethanol Extract of Unripe Annona muricata (l.) Fruits on the Haematological and Histopathological Parameters in Swiss Albino Rats Infected with Salmonella typhi
Background: In addition to the problems of resistance to commonly used antibiotics, toxicity depicts the state of adverse effects caused by the interaction of toxicants with cells. Similarly, blood components are exposed...
Prevention of Pioglitazone Induced Weight Gain by Co Administration of Piperine
Aim: Diabetes is the most common and one of the leading causes of mortality among non communicable diseases. Pilogitazone is the potent PPARr agonist used for the treatment of diabetes. The drug is associated with a subs...