COMPARATIVE PHYSICAL STUDIES OF ATENOLOL BRANDS AVAILABLE IN LIBYAN DRUG MARKET
Journal Title: Innoriginal: International Journal Of Sciences - Year 2016, Vol 3, Issue 1
Abstract
Atenolol is a cardioselective beta1-adrenergic receptor blocking agent prescribed for treatment of hypertension, angina pectoris and cardiac arrhythmias. However, there are many Atenolol brands marketed in Libya. The objective of this study was to evaluate the quality of five commercial Atenolol (100 mg) products available on the Libyan market. We carried out a survey on the price of all Atenolol tablet products and assessed their quality. To assess quality, all products were examined visually for their organoleptic properties, tested for weight uniformity, friability, disintegration, and moisture content assayed. We carried out a physical comparison of all Atenolol tablet products and assessed their quality. To assess quality, all products of Atenolol such as: Atenolol tablets, Actavis United Kingdom, Totamol tablets WOCKHARDT , United Kingdom, Atenolol Normon Spain, Atenolol Film Coated tablets, BRISTOL, United Kingdom and Hypoten tablets, HIKMA Amman–Jordan. Based on our testing procedure, all Atenolol five brands were showed the fulfilment of the compendial specification for uniformity of weight, disintegration and limit of moisture content, except in case of hardness test all the brands showed softer than Hypoten tablets. All the brands are within their expiry dates but there is major difference in price.
Authors and Affiliations
Abdulrhman. A. Akasha, Mokthar. El-baser, Rawan. M. Bondoq, Sakina. M. Saud
Keywords
Related Articles
- EP ID EP443077
- DOI -
- Views 194
- Downloads 0
THE PROTECTIVE EFFECT OF PANDANUS AMARYLLIFOLIUS LEAVES EXTRACT ON PARACETAMOL-INDUCED HEPATOTOXICITY
Objective: This current study was carried out to investigate the hepatoprotective activity of Pandanus amaryllifolius on paracetamol-induced male rats. Methods: Thehepatoprotective activity of ethanol extract of P. amary...
NATIVE SPECTROFLUORIMETRIC DETERMINATION OF AMPROLIUM IN BULK AND PHARMACEUTICAL FORMULATION
Objective: The manuscript discussed the application of a simple, accurate and precise spectrofluorimetric method for determination of amprolium in bulk and pharmaceutical formulation. Method: The emission was measured at...
SUSTAINABLE MINING ACTIVITY IN THE NELLORE MICA BELT THROUGH EXPLORATION OF COLTAN DIPOSIT
Coltan is a dull metallic ore found in major quantities in the Nellore mica belt and also found in eastern areas of the Congo possesses 80 percent of the world’s coltan. Biswas (1935) [1] made an examination of the pegm...
A BRIEF PHARMACEUTICAL REVIEW ON FAST DISSOLVING TABLET
Tablet swigging trouble essentially influences the geriatric and pediatric populaces though the unpalatable taste of medications prompts persistent resistance. Swallowing issues additionally are regular in youthful peopl...
A RESEARCH STUDY ON SYNTHESIS, CHARACTERIZATION AND ANTI MICROBIAL ACTIVITY OF SLIVER NANO PARTICLES USING ECHINOCHLOA COLONA LEAF EXTRACT
Silver-Nano Particles are nano particles of silver i.e. silver particles of between 1nm and 100nmin size. Aim: To develop a facile and eco- friendly method for the preparation of silver nano particles. Materials: In the...