Comparative Randomized Controlled Blind Study of the Anti-Shivering Effect of Hydrocortisone, Granisetron and Meperidine in Post-Spinal Anesthesia in Patients Undergoing Cesarean Section

Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 71, Issue 3

Abstract

<span>Background: </span><span>it was observed that a considerable proportion of patients undergoing surgery experience intraoperative and postoperative hypothermia and it was found that misregulation of body temperature due to anesthesia as well as the cold temperature of the operation room were the main cause.<br /> </span><span>Purpose: </span><span>to compare the anti-shivering effect of meperidine, hydrocortisone and granisetron after spinal anesthesia during elective cesarean section. </span><span>Patients and Methods: </span><span>this study presents a placebo-controlled prospective randomized blind study. Included patients were randomly (using computer generated randomization table) allocated into four equal groups each group consists of 28 patients. </span><span>Results: </span><span>in our study, age, sex, and ASA grade distribution of patients were nearly identical in the four groups. Furthermore, the duration of surgery and amount of irrigation </span><span>fluid used in the four different groups were also similar. We </span><span>did not observe a change in temperature gradient between the four groups. A study with a more prolonged duration of postoperative temperature monitoring is needed to note if core-periphery temperature changes occur with passage of time. </span><span>Conclusion: </span><span>the results indicate that IV granisetron 40 μg/kg was effective as IV meperidine 0.4 mg/kg and both are slightly effective than IV hydrocortisone 2 mg/kg in reducing the incidence and intensity of shivering during spinal anesthesia compared to control group.<br /> </span>

Authors and Affiliations

Eman Helal

Keywords

Related Articles

Specific IgE Immunoassay for House Dust Mites by Using Multiple Allergen Simultaneous Test (MAST) in Asthmatic Children

Background: house dust mites are considered as a major cause of bronchial asthma in young children. Inhalation of dust mite allergens by hypersensitive individuals can result in acute attacks of bronchial asthma. Multipl...

The Use of Intra-Operative Nerve Monitoring (IONM) in Thyroid Surgery to Reduce Recurrent Laryngeal Nerve Injury

Objectives: To assess the relation between use of Intraoperative nerve monitoring (IONM) in thyroid surgery and the prevalence of RLN injury, and to assess its significance of IONM in reduction of RLN injury among patien...

Maternal Serum Amyloid A level in Pregnancies Complicated with Preterm Premature Rupture of Membranes

Background: serum amyloid A (SAA) is a cytokine-inducible acute-phase reactant whose plasma concentrations can exceed 1 mg/mL during an acute-phase response (500 to 1000 fold of plasma levels greater than in the non inf...

Study of Hand Hygiene Awareness among Doctors and Nurses in King Abdulaziz Specialist Hospital

<strong>Background:</strong> hand hygiene is now regarded as one of the most important element of infection control activities. It is an effective strategy to prevent health care-associated infections (HCAIs). It is a re...

Role of Intravenous Hyoscine Butylbromide Injection on The Duration and Progress of First Stage of Labour in Primigavidae

Background: Labour is a physiologic process that results in expulsion of the products of conception outside the uterus throughout 3 stages. It is achieved with changes in the biochemical connective tissue and with gradua...

Download PDF file
  • EP ID EP583881
  • DOI -
  • Views 101
  • Downloads 0

How To Cite

Eman Helal (2018). Comparative Randomized Controlled Blind Study of the Anti-Shivering Effect of Hydrocortisone, Granisetron and Meperidine in Post-Spinal Anesthesia in Patients Undergoing Cesarean Section. The Egyptian Journal of Hospital Medicine, 71(3), 2759-2764. https://europub.co.uk/articles/-A-583881