Comparative studies on mydriatic effect of tropicamide 0.8% and phenylephrin 5.0% in teenagers & geriatric people
Journal Title: International Journal of Research in Hospital and Clinical Pharmacy - Year 2019, Vol 1, Issue 2
Abstract
Prospective study on the comparison of mydiriatic effect of Tropicamide 0.8% and Phenylephrine 5% in teenagers and geriatric people was carried out in suthrama Eye Hospital madanapalle, India. The main objective of this study was to compare the mydriatic effect of a combination of drug in teenagers and geriatric people. It also evaluated the ADR’s produced and the efficacy of the drug in two age groups. In this study population majority of the subjects were female in group A and male in group B. Among the whole population under study in group A and B no one has reported with any case of congenital anomalies. A number of ADR’s are reported but no serious adverse events had occurred. The study was carried out in 100 eyes ie. 50 subjects whom are divided into 2 groups based on age. The comparison of mydriatic effect was done in each group after instilling one drop of a combination of 0.08% Tropicamide and 0.5% Phenynilephrine. The pupillary size where measured before and after administration of drug and the results were compared. The results showed that there is a large difference in the normal pupil size between teenagers and geriatric people. After dilation the difference in pupil size was statistically significant among the two groups. The study concludes that the pupillary dilation produced by administering 0.8% Tropicamide and 5% Phenylephrine produces higher mydriatic effect in teenagers than geriatric people.
Authors and Affiliations
K. Diwakar , Y. Sailaja , V. Palanivel , Shaik Baba Fakruddin , T. Gangadhara , B. Syed salman
Students initiated ADR reporting activity in pharmacy colleges - a survey
ADR monitoring is an important function of many pharmacists working in the clinical field. The aim of this study is to assess the student knowledge about Pharmcovigilance and activities done in ADR centers and to find ou...
Impact of pharmacist provided knowledge on dengue among selected school children
Background: Dengue is a self-limiting acute mosquito transmitted disease caused by an arbovirus and spread by Aedes mosquitoes, sever infections results in DHF & DSS. Hence school education has been described as a ‘s...
To evaluate safety and efficacy of tedizolid phosphate in the management of several skin infections
Tedizolid Phosphate is an oxazolidinone-class antibiotic and is used for the treatment of acute bacterial skin and skin structure infections. it is a prodrug activated by plasma or intestinal phosphatases to tedizolid fo...
Evaluation and effect of patient counseling by Pharm D students in hospitals - a survey
Patient understanding about the illness is very important role in management .Counseling makes the patient understand his/her illness, lifestyle modifications in better way and enhance patient compliance. The objective o...
The self-medication practice in primary dysmenorrhea among pharmacy students-a cross-sectional questionnaire study
Primary dysmenorrhea is one of the most common gynecological problems among adolescent females which interferes with daily activities, affecting their physical and emotional aspects and has a negative impact on the quali...