Comparative study between intralesional MMR and intralesional BCG in treatment of verruca vulgaris
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: Cutaneous warts are common dermatological conditions caused by the human papilloma virus (HPV). Immunotherapy has now found a significant place in the treatment of warts because of its non-destructive action, ease of use, and promising results. Objectives:To compare efficacy between intalesional MMR and BCG in treatment of verruca vulgaris. Method: 30 Patients were included in study and divided into two groups. Group1:This group included 15 patients subjected to intralesional MMR. Group 2:This group included 15 patients subjected to intralesional BCG. Only single wart was injected at 2-weeks interval until complete clearance or for a maximum of 5 treatments. Follow up of patients was done every month for 3 months for clinical assessment of results and to show any recurrence. Results: In group1: 73.3% of patients showed complete lesional clearance and 46.6% showed distant lesional clearance . 6% showed erythema around lesion & 26.6% showed hyperpigmentation. In group 2:33.3% showed lesional clearance and 13.3% showed distant lesional clearance. 60% of patients showed lesional ulceration and 30% showed flu like symptom & 53.3% showed hyperpigmentation. There is statistically significant differance (p<0.05) between both groups where MMR showed higher efficacy than BCG. Conclusion:. We found that the treatment of common warts by intralesional MMR vaccine is effective, with good cure rates, and excellent safety profile compared to intralesional BCG.
Authors and Affiliations
Dr. Pooja. Munnangi, Dr. J. Ch. K. L. P. Kishore, Dr. V. Nivedita Devi
Keywords
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- EP ID EP362432
- DOI 10.9790/0853-1702074450
- Views 43
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