COMPARATIVE STUDY BETWEEN VARIOUS TOPICAL AGENTS IN PROMOTION OF WOUND HEALING IN DIABETIC FOOT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 30
Abstract
BACKGROUND Foot care amongst diabetics is incredibly important, as foot related complications are common. Majority of diabetic patients develop foot ulcer at one point of time or the other during the course of the illness. Foot ulcers and amputations are the major cause of morbidity, disability as well as emotional and physical cost for people with diabetes. Therefore, routine dressing plays an important role in healing. Traditional form of dressing in diabetic foot is done with Normal Saline. Wide variety of new dressings have been developed. The aim of this study is to compare the efficacy of topical agents namely normal saline, phenytoin, placental extract and collagen dressing in promotion of wound healing in diabetic foot ulcer. MATERIALS AND METHODS This is a non-randomised controlled trial, done over a period of 5 months from August 2013 to December 2013 in Madras Medical College Hospital, Tamilnadu. 120 patients with diabetic foot ulcer were selected randomly and divided into four groups and topical agents of normal saline, phenytoin, placental extract and collagen sheets were applied. Patients were prospectively analysed for wound healing. Phenytoin dressing compared with other dressings has good and faster healing rate in diabetic foot ulcer. Methodology- This is a non-randomised controlled trial. The patients who were admitted in Department of General Surgery, Madras Medical College Hospital, Tamilnadu, tertiary care teaching institution during the study period were screened. 120 patients were randomly divided into 4 groups and treated with normal saline, phenytoin dressing, placental extract and collagen dressing. The factors studied were reduction in ulcer size, culture on day 10, need for second debridement and time for granulation. RESULTS Phenytoin dressing promoted rapid wound healing and also needed lesser repeat debridement and lesser hospitalisation compared to other agents in study. CONCLUSION Topical phenytoin is a novel cost-effective agent in diabetic foot ulcer for rapid wound healing reducing the morbidity and ensure faster return to normal day-to-day activities.
Authors and Affiliations
Umesh Raj Somasundaram, Sabarimalai Palanisamy
Keywords
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- EP ID EP538922
- DOI 10.14260/jemds/2018/774
- Views 86
- Downloads 0
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