COMPARATIVE STUDY OF 0.125%BUPIVACAINE VERSUS 0.125% LEVOBUPIVACAINE FOR LABOR ANALGESIA
Journal Title: IJAR-Indian Journal of Applied Research - Year 2017, Vol 7, Issue 5
Abstract
Background: A clinical study was undertaken in 60 parturients in labor. All parturients were of ASA1 without any associated systemic disease who are in active labor with 0.125% bupivacaine and 0.125% Levobupivacaine to compare onset of analgesia, maximum level of sensory blockade, duration of analgesia. Methodology: ey are allocated randomly into the two groups: Group-I and Group-II, 30 members each, to compare the effectiveness of Bupivacaine and Levobupivacaine. In Group I total number of paturients 30 received 0.125% bupivacaine 10 ml alone as initial bolus dose and 0.125% bupivacaine 5ml as top up doses. In Group II total number of parturients 30 received 0.125% levobupivacaine 10 ml alone as initial bolus doses and 0.125% levobupivacaine 5 ml as top up doses. Results: From our study: 1. The onset of analgesia with 0.125% levobupivacaine (6.53) which was similar to the onset time for the same concentration of bupivacaine (6.8 min) 2. 10 ml of 0.125% bupivacaine or 10 ml of 0.125% levobupivacaine produces a maximum level of sensory blockade up to T6 3. The duration of analgesia with 0.125% bupivacaine (80 min) is similar to the duration of analgesia 0.125% levobupivacaine (81 min). Conclusion: Based on the data bupivacaine and levobupivacaine have produced equivalent onset, sensory block, and duration with good maternal and fetal outcome. The analgesic efficacy mainly depends on the concentration rather than the type of anesthetic drug. We conclude that both 0.125% bupivacaine and 0.125% levobupivacaine confer adequate and safe labor analgesia with no significant influence on the mode of delivery, hemodynamic changes, duration of labor or neonatal outcome.
Authors and Affiliations
Dr. K V Mahesh Kumar, Dr P HARISH GAUTAM, Dr KVSL NAGA BHARGAVI
Keywords
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