Comparative Study of Breast lumps by Fine Needle Aspiration Cytology and Core Needle Biopsy

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Comparative Study of Breast lumps by Fine Needle Aspiration Cytology and Core Needle Biopsy

Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 7

Abstract

Breast is the most common site of various lesions that presents as palpable breast lumps including benign, inflammatory and malignant causes. Now a day’s incidence of breast cancer is increasing at its pace causing increase in morbidity in female patients particularly. This has called to initiate a diagnostic modality to detect breast cancers in early phases so as to combat the increasing morbidity due to breast cancers. Mammography is taking lead in early suspicion and detection of breast lumps. But Fine needle aspiration cytology is one of the most effective and specific for diagnosis of breast lumps. But fine needle aspiration cytology do have its own drawbacks and grey zone areas which has put core needle biopsy technique forth to obviate excisional biopsy along with giving advantages of tumor grading, staging and immunophenotypic analysis giving parallel results with that of gold standard histopathological diagnosis. Thus the present study has been conducted with the aim of utility of core needle biopsy in diagnosing breast lumps, comparing it with fine needle aspiration cytology results and initiating use of core needle biopsy as a routine technique wherever applicable. Total 107 cases studies showed maximum number of cases in the age group of 31-50 years of age. bethesda system was applied for reporting spiration cytology smears and core needle iopsy sections in 5 categories as benign, atypia, suspicious for malignancy, positive for malignancy, and unsatisfactory and results were compared. Benign lesions outnumbered malignant one both in fine needle aspiration cytology and core needle biopsy, Fibroadenoma was the most common benign and ductal carcinoma was most common malignant diagnosis given. In the category of intermediate or atypical cases proliferative breast disease was common diagnosis offered on aspiration smears. There were few cases which were diagnosed inadequate on cytology has given definitive diagnosis on core needle biopsy. Few cases which has given benign diagnosis out malignant on core needle biopsy. Histopathological diagnosis was available in 80 cases. Thus core needle biopsy has detected more breast carcinomas with sensitivity of 95.4% as compared to 60.5% sensitivity of aspiration cytology. Due to definitive diagnosis offered by core needle biopsy rate of suspicious lesions decreased replacing use of excisional biopsy.

Authors and Affiliations

Dr. Priyanka Asawa

Keywords

breast lumps core needle biopsy fine needle aspiration cytology.

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EP ID EP619952
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