Comparative Study of Cardiovascular Response to Sustained Handgrip Exercise Test in Stage1 Essential Hypertensive and Normotensive Subjects
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 8
Abstract
Abstract:Hypertension is most prevalent disorder worldwide and it is major risk factor for cardiovascular complications.Our knowledge is still limited about the cause of increased cardiovascular risk in essential hypertension. Autonomic nerves supplying the heart may also be involved in hypertension causing cardiac autonomic neuropathy (CAN).Evaluation of circulatory responses during sympathoexcitatory stress like isometric muscle contraction i.e. sustained hand grip (SHG) is a useful method to assess cardiac function. Therefore the present study was aimedto assess hemodynamic response (blood pressure and heart rate response) during sustained hand grip test in newly diagnosed stage 1 essential hypertensive subjects and compare the same with age, BMI and gender matched normotensive controls. This study was carried out at Department of Physiology, B. J. Medical College, Pune. Fifty newly diagnosed stage 1 essential hypertensive subjects were included in study group and fifty age and gender matched healthy normotensive subjects were included in control group. The difference between the systolic, diastolic blood pressure records (DBP) and heart rate just before the release of contraction at 30% of MVC and just before starting handgrip maneuver, was taken as a measure of sympathetic autonomic cardiac functions. In the present studythe blood pressure response (∆SBP, ∆DBP) and heart rate response (∆HR) were statistically significantly increased (p<0.05) in newly diagnosed stage 1essential hypertensive subjects as compared to normotensive subjects during sustained isometric hand grip test. As there is increased blood pressure and heart rate response during sympathetic stress like sustained handgrip test we concluded that there is increased sympathetic activity in stage 1essential hypertension. Keywords:Hypertension, sustained hand grip test (SHG), cardiac function, sympathetic stress
Authors and Affiliations
Talele PL, Deshpande SV, Badhe YK, Kowale AN, Aundhkar NV
Keywords
Related Articles
- EP ID EP372876
- DOI -
- Views 59
- Downloads 0
A Case of Aneurismal Bone Cyst in Lower End of Tibia
Aneurysmal bone cyst involving the lower end of tibia in middle age male is a rare entity. A 37 years male patient came to the outpatient department with a complaint of pain in the lower part of the right leg since two y...
Is Post-Inflammatory Urethral Stricture Commoner Than Post-Traumatic Urethral Stricture? A Study in South-South Nigerian Hospital
Urethral stricture is a narrowing of the urethra due to scarring process. It can be caused by a pre-existing inflammatory process, traumatic condition to the urethral or idiopathic where the cause is unknown. Historicall...
Etiology and Clinical Spectrum of Pregnancy – Related Acute Kidney Injury
The aim of the present study was to analyze the etiological factors, clinical spectrum and outcome of pregnancy related acute kidney injury. A total of 64 women with pregnancy related acute kidney injury admitted in depa...
Obstructive Sleep Apnea- An Overview
Abstract: OSA occurs due to upper airway obstruction with shallow breathing lasting for 20- 40 seconds during sleep along with decreased blood oxygen saturation. There are various risk factors for OSA like obesity, narro...
Polycaprolactone and polycaprolactone/ chitosan electrospun scaffolds for tissue engineering applications
Scaffold engineering and fabrication techniques play a fundamental role in biomedical engineering applications. Tissue engineering has been considered as a very promising alternative therapeutic strategy compared to trad...