Comparative Study of Clomiphene Citrate and Aromatase Inhibitors (Short and Long Protocols) In Polycystic Ovarian Syndrome
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 7
Abstract
Background: Polycystic ovarian syndrome (PCOS) is a heterogenous disorder and is characterized by excessive androgen production by the ovaries.First line drug for ovulation induction is clomiphene citrate(CC).Insufficient evidence is currently available to recommend the clinical use of aromatase inhibitors for routine ovulation induction. Methods: It was the prospective study of 120 women between 20 -35 years of age who are PCOS with regular follow up in OPD. They were divided into three study groups on the basis of drugs used. Results: Ovulation was better in women on clomiphene citrate and letrozole 5 mg short protocol as compared to women on letrozole 2.5mg long protocol. Conclusions: The rate of ovulation with clomiphene citrate (group A) in PCOS patients is 76% and with letrozole short (group B) and long protocols(group C) it is 64% and 28.8% respectively.The endometrial thickness in clomiphene citrate(group A) in PCOS patients is 8.8 mm and with letrozole short(group B) and long protocol(group C) in PCOS patients it is 10 mm and 10.2 mm respectively
Authors and Affiliations
Swati Garg
Keywords
Related Articles
- EP ID EP513063
- DOI -
- Views 162
- Downloads 0
Analysis of Prescription in the Department of Cosmetic Surgery - According To Who Prescribing Indicators
Cosmetic surgery is a unique discipline of medicine focused on enhancing appearance through surgical and medical techniques. Cosmetic surgery can be performed on all areas of the head, neck and body. Cosmetic surgical pr...
Characterization and management of β- lactamases producing Escherichia coli causing complicated UTIs in an era of antimicrobial resistance
Urinary tract infections (UTIs) are among the most common infectious diseases in the community as well in healthcare settings.1 A complicated UTI is defined as an infection of urinary tract that is associated either with...
Neonatal Death and Morbidity in Second Twins.
Background: The second twin is generally considered at higher risk of severe morbidity and mortality because of obstetric complications that may occur after delivery of the first twin. Methods: The hospital based descrip...
Comparative Study between Non Descent Vaginal Hysterectomy and Abdominal Hysterectomy- A Prospective Study.
Introduction: Hysterectomy is the most common major gynaecological surgery. Can be done by abdominal or vaginal route or laparoscopically. Laparoscopically assisted vaginal hysterectomy (LAVH) is increasing,but is cost...
Effects of dengue infection on pregnancy outcome
Background: Dengue is a vector transmitted viral infection; tropical and subtropical countries see outbreaks of dengue each year. Dengue infection in pregnancy carries the risk of haemorrhage for both the mother and the...