COMPARATIVE STUDY OF DEXMEDETOMIDINE AND MAGNESIUM SULPHATE AS AN ADJUVANT TO BUPIVACAINE IN SPINAL ANESTHESIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 35
Abstract
spinal anaesthesia is a widely used simple anaesthethetic technique providing adequate analgesia and muscle relaxation. Search for an adjuvant providing satisfactory intra and post-operative analgesia is still continuing. This study aims to compare the dexmedetomidine and magnesium sulphate as an adjuvant to spinal anaesthesia. MATERIAL AND METHODS: After obtaining institutional ethical committee approval and written informed consent from patients 90 ASA grade I &II patients of either sex having height between 140-180 cm and weight between 40-90 kg were randomly divided in 3 groups of 30 patients each (n=30). Group C: Received 3.0 ml 0.5% bupivacaine heavy + 0.5 ml NS. Group M: Received 3.0 ml 0.5% bupivacaine heavy + 50 mg MgSO4 diluted to 0.5 ml of NS. Group D: Received 3.0 ml 0.5% bupivacaine heavy 10 +dexmedetomidine 10µg diluted to 0.5 ml NS. RESULTS: onset of sensory and motor block was delayed in Group M as compared to group D and group C. Onset of sensory and motor block in group D was significantly faster as compared to group C and group M. Total duration of sensory anaesthesia, duration of sensory block and duration of motor block was significantly prolonged in group D as compared to group M and group C. Patients were hemodynamically stable in all the groups. There were no incidences of any significant adverse effect in any group. CONCLUSION: intrathecal dexmedetomidine is a better adjuvant to intrathecal bupivacaine because of rapid onset of sensory and motor blockade and prolonged duration of sensory and motor blockade without any potential side effects.
Authors and Affiliations
Rakesh Kumar Singh, Vishal Vaibhaw, Sabir Hasnat
Keywords
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- EP ID EP231917
- DOI 10.18410/jebmh/2015/756
- Views 137
- Downloads 0
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