Comparative study of effectiveness of Sublingual Misoprostol (600mcg) versus Intramuscular Oxytocin (10U) in AMTSL(Active Management of Third Stage of Labour)
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Objective: To compare the effectiveness of sublingual misoprostol(600µg)versus Intramuscular Oxytocin(10IU) in the active management of 3rd stage of labour and to study the blood loss and side effects in both the groups. Materials& Methods: This study was conducted in the Department of Obstetrics& Gynaecology at Government General Hospital, Guntur during the period of March 2016 to August 2017 in low risk vaginal deliveries adhering to certain inclusion and exclusion criteria .A total of 200 cases were studied with 100cases in each group. Group-I were given 3 tablets of misoprostol200µg each and Group-II were given inj.Oxytocin 10IU intramuscular after cord clamping and cutting. Data regarding age, parity, amount of blood loss, predelivery and postdelivery Hb levels, need for additional oxytocics, side effects, postpartum complications were taken and analysed. Results: The average blood loss was 217.9ml in misoprostol group compared to 233.45ml in oxytocin group. The fall in haemoglobin percentage was 0.9g/dl and 0.8g/dl respectively. The difference in observation of both groups was statistically not significant(p>0.05).The incidence of PPH was 2% in both the groups. The need for additional oxytocics was also 2% in both the groups. Shivering and pyrexia were the commonest side effects noted in misoprostol group. Conclusion: Both sublingual misoprostol and intramuscular oxytocin were equally effective in the active management of 3rd stage of labour
Authors and Affiliations
Dr. K. Swarupa Rani, Dr. P. Lavanya.
Keywords
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- EP ID EP244873
- DOI 10.9790/0853-1610157377
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