Comparative Study of Efficacy of Ciprofloxacin and Ceftriaxone in Typhoid Fever
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 2
Abstract
Typhoid fever is an acute systemic disease. It is caused by Salmonella typhi. The disease is unique to humans. In 1880, Ebreth first isolated the causative organism. The disease has worldwide in distribution and endemic in Tropical Countries. Between 15 and 35 years of age incidence of disease is more. Typhoid had been prevalent in many parts of India and is resistant to chloramphenical, ampicillin, co-trimaxazole. The use of quinolones in children has been prevalent. The Ciprofloxacin used in children are not free from adverse effects. The resistant cases requires Cephalosporins. Currently the III generation cephalosporins like ceftriaxone and cefotaxime are used in multi drug resistant typhoid fever. These drugs are bactericidal and are very effective. The aim of the present study is to compare the efficacy Ciprofloxacin and Ceftriaxone in treatment of Typhoid fever. Patients who attended the department of Medicine with fever were selected. They were divided into two groups. 25 patients were treated with ceftriaxone under Group – I and another 25 patients were treated with Ciprofloxacin under Group – II. The results of both groups were recorded. There were significant differences observed among patients in the two groups with regard to age, sex, duration of fever before admission and clinical findings. The mean number of days for patients to become afebrile was significantly lowered in those receiving ceftriaxone (P < 0.001) than in those receiving Ciprofloxacin. Ceftriaxone in the treatment of typhoid fever was proved safe and effective in the present study
Authors and Affiliations
Dr. M. Usha Rani
Keywords
Related Articles
- EP ID EP210772
- DOI -
- Views 87
- Downloads 0
Compendium of Urinalysis – Urine Reagent Strips and Microscopy
Background: Urine examination also referred to as liquid renal biopsy has provided valuable clinical information about the functional status of the kidney. These results can be relied for a number of applications, includ...
Role of Diagnostic Laparoscopy in non Specific Abdominal Pain
Background: Diagnostic Laparoscopy provides us with good view of whole peritoneal cavity there by clinching diagnosis. In General population Appendicular pathology is the leading etiology of non specific abdominal pain,...
Study of Peptic Ulcer Perforation in 80 Cases
Peritonitis following perforation of digestive tract remains an important problem in the field of surgery. In this study of 80 cases, males were(86.25%)and females were (13.75%).Common age of peptic ulcer perforation bei...
Ventral Onlay Buccal Mucosal Graft Urethroplasty Based on Tunica Vaginalis Flap for Balanitis Xerotica Obliterans Related Urethral Strictures: The Outcome of Single- Stage Reconstruction
Background: Balanitis xerotica obliterans (BXO) related urethral strictures treatment demand particular attention to cosmesis and urethral patency. Usually a single or two- stage urethroplasty is needed in such cases. We...
Ewing’s Sarcoma in a Rural Medical College Hospital in West Bengal- A Retrospective Study
Objective: To outline the epidemiological profile and prognostic factors for Ewing's sarcoma in a rural medical college in hilly area in West Bengal Material and Methods: The medical records of 27 patients with Ewing's s...