Comparative Study of Epidural Ropivacaine HCL-Fentanyl Citrate and Ropivacaine HCL-Tramadol HCL for Postoperative Analgesia in Abdominal Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 9
Abstract
Introduction: Central neuraxial adjuvant drugs, alone or in combination, are used intrathecally or epidurally for the treatment of acute and chronic painful conditions. Aims: To compare the efficacy and duration of analgesia as well as to compare the hemodynamic parameters and the adverse effects of study drugs. Method: 100 adult patients of ASA grade I and II, of either sex, belonging to 18 -65 years of age, posted for elective abdominal surgeries were selected for the study. Patients were randomly divided into two groups of 50 each. Group RT received 13ml of Inj. Ropivacaine hydrochloride (0.2%) + 1ml of Inj. Tramadol hydrochloride (50mg) + 1ml of Normal Saline. Group RF received 13ml of Inj. Ropivacaine hydrochloride (0.2%) + 0.5ml of Inj. Fentanyl citrate (25µg) + 1.5ml of Normal Saline. Total volume = 15 ml, by epidural route at the time of skin closure. Postoperatively, VAS Score at rest and movement, Ramsay sedation score, hemodynamic changes and adverse effects were noted. Result: VAS at rest and movement were higher in Group RF at 6 hrs whereas in Group RT at 10 hrs. Ramsay sedation score were also comparable at 6 hrs and 10 hrs. Duration of analgesia was around 8 to 10 hours in Group RT whereas it was around 6 to 8 hours in Group RF. Conclusion: Epidural Tramadol hydrochloride along with Ropivacaine hydrochloride provides significant longer duration of analgesia, lower pain scores as compared to Epidural Fentanyl citrate with Ropivacaine hydrochloride.
Authors and Affiliations
Surekha Shaboo
Keywords
Related Articles
- EP ID EP538871
- DOI 10.21088/ijaa.2349.8471.5918.10
- Views 68
- Downloads 0
Sevoflurane with Halothane for Endotracheal Intubation in Paediatric Patients: A Comparative Evaluation
In paediatric patients, smooth induction with rapid endotracheal intubation without morbidity and mortality is of prime importance. Many of the inhalational anaesthetic agents have been tried for this purpose. In the pre...
Are We Performing Hand Hygiene: A Lifesaving Skill Correctly?
This question is asked invariably just like being asked during CPR’s correct method and right timing of practicing hand hygiene to avoid a loss of life to hospital acquired infection (HAI). Are we doing enough? Are we re...
Supraclavicular Brachial Plexus Block: A Comparative Clinical Study between Bupivacaine and Levobupivacaine
The racemic bupivacaine is commonly used local anaesthetic drug brachial plexus block in as it provides longer duration of action but has risk of cardiotoxicity .The use of levobupivacaine in brachial plexus block seems...
A Comparative Study between Intrathecal Bupivacaine with Clonidine vs Bupivacaine with Neostigmine for Vaginal Hysterectomies: A Randomized Double Blinded Study
Introduction: Vaginal hysterectomy is the most common surgery done under spinal anaesthesia. The combination of local anaesthetics with adjuvants is getting more popular for better post-operative analgesia. Aim: The pur...
Effect of use of oral Pregabalin as an adjunct in Spinal Anaesthesia
Pain relief with minimal side effect in post operative surgical patients is essential for early mobility and recovery. Objective: This study was conducted to find out whether preoperatively oral pregabalin used as an adj...