COMPARATIVE STUDY OF INTRA-ARTICULAR HYALURONIC ACID AND INTRA-ARTICULAR TRIAMCINOLONE HEXACETONIDE IN PRIMARY OSTEOARTHRITIS OF KNEE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 50
Abstract
BACKGROUND Intra-articular (IA) corticosteroid injection has an established therapeutic role, but the effect is short lasting. IA Hyaluronic acid (HA) is considered as a therapeutic alternative in patients who have failed non-pharmacologic and analgesic treatment. Aim of the study is to compare the efficacy and safety of IA HA with Triamcinolone hexacetonide (THA) in treatment of primary osteoarthritis (OA) knee. MATERIALS AND METHODS A descriptive cross-sectional study was done among 30 patients. One group (n=15) received IA THA 20 mg/2 mL on day 0 and other group (n=15) received IA HA 20 mg/2 mL on day 0, 7 &14 under aseptic precautions. The efficacy assessment using KGMC Score for pain, disability and functional impairment was done in 0-100 mm scale. Side effects if any were noted. RESULTS The present study revealed IA THA has superior short-term efficacy compared to IA HA. But HA has got long term superior efficacy. CONCLUSION OA being a chronic disease process, we need a drug which has a long lasting effect. Additive effect of HA & THA can be considered for better efficacy.
Authors and Affiliations
Sabeena Kizhedath, Haseena Kizhakkan Abboobacker, Gopesh Valoth, Bindhu Vasudevan
Keywords
Related Articles
- EP ID EP219653
- DOI 10.14260/Jemds/2017/830
- Views 66
- Downloads 0
PREVALENCE OF PERIODONTAL DISEASE IN WOMEN WITH POLYCYSTIC OVARY SYNDROME- A COMPARATIVE DESCRIPTIVE STUDY
BACKGROUND Polycystic ovary syndrome (PCOS) is a common disorder affecting 4% to 12% of women of reproductive age. Increased production of steroid hormones is associated with increased gingival inflammation. Thus, the pr...
A COMPARATIVE STUDY OF LOW DOSE INTRAVAGINAL MISOPROSTOL (PGE1) WITH INTRACERVICAL DINOPROSTONE (PGE2) GEL FOR CERVICAL RIPENING AND LABOUR INDUCTION
[b]OBJECTIVES[/b]: (1) To compare the efficacy of low dose PGE1 with PGE2 for induction of labour at term. (2) To compare the safety of PGE1 with PGE2 in terms of labour and neonatal outcome.[b] METHODOLOGY[/b]...
CLINICAL PROFILE OF ENTERIC FEVER IN CHILDREN
BACKGROUND The protean manifestations of enteric fever make this disease a true diagnostic challenge. Untreated enteric fever is a grueling illness that may progress to delirium, obtundation, intestinal hemorr...
PREVALENCE OF POSTEROLATERAL CORNER INJURIES IN MRI DETECTED ANTERIOR CRUCIATE LIGAMENT INJURIES
BACKGROUND Anterior cruciate ligament injuries contribute to the major ligament injuries involving the knee. What we thought of isolated anterior cruciate ligament (ACL) injuries were not isolated injuries, there are ass...
RUPTURED POSTERIOR COMMUNICATING ARTERY ANEURYSM IN A PRIMIGRAVIDA
PRESENTATION OF CASE A 20-year-old primigravida at 8 weeks of gestation presented to us with history of drooping of the right upper eyelid. It was associated with pain over the upper part of right side of face. She had h...