Comparative study of intralesional BCG and PPD in the treatment of multiple cutaneous warts
Journal Title: IP Indian Journal of Clinical and Experimental Dermatology - Year 2018, Vol 4, Issue 1
Abstract
Introduction Multiple cutaneous warts are often asymptomatic cosmetically disfiguring and difficult to treatnbspwith conventional modalities hence immunotherapeutic modalities can be used in such cases There are no comparitive studies with immunotherapeutic modalities for the treatment of multiple andnbsp extensive warts This study aims to compare the efficacy and safety of intralesionalnbsp BCG and PPD in the treatment of multiple cutaneous wartsMaterials and Methods It is a double blinded randomized clinical trial involving thirty patients having more than ten cutaneous warts with a positive mantoux reaction The patients were randomly allocated into twonbsptreatment groups group A PPD and group B BCG Intralesional injections were given at two weekly intervals till complete clearance of all the warts or for a maximum ofnbspfour sessions in both thenbsp groups Response in injected warts andnbsp distant warts was assessed at each visit and sequential clinical photographicnbsprecords were maintainedResults Thirty patients withnbsp positive mantoux reaction were enrolled for thenbsp trial 17 patients in group A PPD and 13 patients in group B BCG Complete resolution of lesions was noted in 353 in PPD group and 308 in BCG group and partial resolution was noted in 470 and 384 in PPD and BCG group respectivelyConclusion Intralesional PPD showed marginally better results than intralesional BCG in the treatment of multiple cutaneous warts Majority of the patients treated with BCG had tender nodule at injection siteKeywordsnbspImmunotherapy Multiple warts Intralesional BCG Intralesional PPDnbspnbspnbspnbsp
Authors and Affiliations
Rajashekar T. S. , Amulya R, Sathish S, Suresh Kumar
Keywords
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- EP ID EP488939
- DOI 10.18231/.2018.0001
- Views 98
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