Comparative Study of Lipid Profile among Stroke Patients with Gender Variations
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 1
Abstract
Stroke is defined according to WHO as rapidly developing clinical signs of focal disturbance of cerebral functions with symptoms lasting for 24hrs or longer or leading to death, with no apparent cause other than vascular origin. This study was aimed to find out the association of one common risk factor of cardiovascular complication risk factor namely lipids level in stroke patient. And the main course of the study is to find the lipid level variations among both genders of stroke population. The stroke patients who were admitted in the Stroke ward of Department of Neurology, SRMC&RI were recruited in this study Patients with diagnosis of stroke comprising 50 consecutive patients of both the genders of age group around 21-60 yrswere included in the study while patients on lipid lowering therapy were excluded from study. A serum sample after 12 hours of overnight fasting was taken on the both groups of patients. Total serum cholesterol, triglycerides, LDL cholesterol, VLDL-cholesterol and HDL-cholesterol was determined, using enzymatic colorimetric method.Statistical analysis - Done by comparison of lipid profile in two subgroups, using proportion test for any significant differences . From our study we concluded that females are in high risk for prevalence of cardiovascular disease. Total serum cholesterol was high in female stroke patient’s 210±32.92 mg/dl when compared to male stroke patient’s 190±25.82 mg/dl which is statistically significant.Total triglycerides were increased in femalesstroke patients because of high body mass index when compared to male stroke patients was around 213±23.92, 197±58.43 mg/dlwhich is statistically significant.HDL-cholesterol level were very low in female stroke patients when compared to male stroke patientsthis is statistically more significant. The values were around 23.72±12.06, 37.43±7.18 mg/dl. LDL cholesterol is the direct marker of large vessel obstruction. LDL cholesterol level was found to be more in femalestroke patients when compared to malestroke patients. The values are 141.81±31.89, 123.92±33.73 mg/dl. VLDL-cholesterol was high in femalestroke patients when compared to male stroke patients which arestatistically significant the values are 44.93±8.75, 37.83±9.33 mg/dl. Keywords: Stroke, Cardiovascular diseases, Total serum cholesterol, Triglycerides, LDL -cholesterol, VLDL-cholesterol and HDL-cholesterol.
Authors and Affiliations
Anbuselvan V, Padmavathi R, Velmurugendran CU, Shyamala Ramnath, Jayachandran Paulswamy
Keywords
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