Comparative Study of Low Dose Magnesium Sulphate Versus Standard Regime In Severe Preeclampsia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
In this study a comparison was made between two different dosing schedules of Magnesium Sulfate with respect to prevention of fits primarily, when applied to two groups of severely preeclamptic women. We conducted the study on 150 severely preeclamptic women at third trimester carrying singleton pregnancy, and were randomly allocated into two groups, Group L and Group S. Group L received only 5 gm I.M. loading dose with 2.5 gm I.M. maintenance dose of Magnesium Sulfate, whereas Group S received the standard Prichard regime. This study revealed the incidence of eclampsia to be 3% and 4% in Group L and Group S respectively. Spontaneous vaginal delivery was the outcome in 73.33% and 77.33% in Group L and Group S respectively. Twenty (20) women (26.66%) and 17 women (22.66%) were delivered by Cesarean section in Group L and Group S respectively. These outcomes were statistically insignificant. Non progress of labour was the major indication of LSCS in both Group L and Group S. This outcome is also statistically insignificant. Among the maternal side effects, hematuria, blurred vision, nausea & vomiting, oliguria, respiratory depression and loss of knee jerk were noticed in both Group L and Group S and appeared to be statistically insignificant.Apgar score at 5 minutes and duration of stay in NICU were considered as two parameters to compare neonatal outcome between the two groups. 89.33% neonate in Group L and only 93.33% in Group S had Apgar score more than 7. This appeared statistically insignificant. 10.66% neonates in Group L and 6.66% in Group S had Apgar score less than 7. This also appeared statistically insignificant. Duration of stay in hours in NICU appeared more in Group L than Group S but appeared statistically insignificant. Thus from the above results, low dose of Magnesium Sulfate appeared equally effective in preventing eclampsia in severely preeclamptic women in comparison to the Pritchard regime. Feto-maternal side effects were noticed less in low dose group, thus favoring its use in clinical practice.
Authors and Affiliations
Dr. Himadri Nayek, Dr. Faruk Hassan, Dr. Satabdi Mondal, Dr. Debarshi Jana
Keywords
Related Articles
- EP ID EP556736
- DOI 10.9790/0853-1803114247.
- Views 89
- Downloads 0
Quality of life in patients undergoing treatment for breast cancer at a tertiary care hospital.
Background:Understanding the effect of breast cancer treatment on a patient's quality of life (QOL) has been a central clinical and research question.Aims And Objectives:To study of QOL of women admitted to Goa Medical C...
Percutaneous Nephrolithotomy (PCNL): A Single-Centre Experience
Objective: The purpose of this study is to present an experience gained at a centre on PCNL and its outcome Methodology: A prospective study of patients who underwent PCNL during the period of October, 2016 to February,...
Chest X Ray findings in New Sputum Positive Pulmonary Tuberculosis
Background: Tuberculosis remains a worldwide public health problem. The guidelines of RNTCP suggest sputum as the initial diagnostic test for Tuberculosis. If sputum test is positive in patients who are receiving Anti tu...
An Opinion Survey on Medical Education Technologies Prevalent And Innovative
The aim of the study is to find a suitable teaching method that focuses on both students and teachers and that focuses on both students and teachers and that yields the best out of the teaching learning process. A cross-...
Therapeutic Efficacy of Peritoneal Dialysis in Pediatric Acute Kidney Injury Patients in a Referral Hospital
Background: Acute Kidney Injury(AKI) in children is associated with significant morbidity and mortality. Peritoneal dialysis (PD) is the preferred and convenient treatment modality for acute kidney injury (AKI) in childr...