Comparative study of Misoprostol (PGE1) and Dinoprost gel (PGE2) for cervical ripening in induction of labour in postdated pregnancy
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Comparative study of intracervical Dinoprost gel (PGE2) and intravaginal misoprostol (PGE1) in cervical ripening for induction of labour. The need for other method of augmentation of labour like oxytocin infusion. The perinatal and maternal outcome in both. It is a clinical prospective study conducted in Department of Obstetrics and Gynaecology, Kamla Raja Hospitals, Gwalior from 1st Jan 09 to 30 June 09.We divided 100 postdated women in two groups: Group 1 : Misoprostol (PGE1), Group 2 : Dinoprost gel (PGE2), Among 100, women 50 women given Tab. Misoprostol and 50 women dinoprost gel. Gestation greater than 41 weeks. Vertex presentation with single fetus. Bishop score less than 6. No cephalopelvic disproportion. No history of renal disease, bronchial asthma, heart disease. 1st trimester USG for confirmation of EDD were used in study and excluded those having Transverse lie or presentation other than cephalic. Previous operation on uterus. Placenta previa. Polyhydramnios. There was significant difference in induction-established labour interval in both groups (p<0.05). Induction delivery interval was shorter in PGE1 group than PGE2. Less no. of patients in PGE1 group required oxytocin augmentation than PGE2 group. No significant difference in neonatal outcome in either group. secret of success in labour induction lies in replicating the process of spontaneous parturition as closely as possible. Use of PGE1 is a less invasive more natural event then PGE2 gel which requires intravenous oxytocin infusion more. To reduce the maternal morbidity and mortality in postdated pregnancy misoprostol is very effective, long lasting and very potent drug. It is a promising drug for labour induction.
Authors and Affiliations
Dr. Archana Maurya, Dr. Vibha Moses
Keywords
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