Comparative study of nebulized lignocaine with intravenous lignocaine on stress response to endotracheal intubation
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 8, Issue 2
Abstract
Direct laryngoscopy and endotracheal intubation result in hemodynamic changes which may lead to increased morbidity and mortality. The present interventional study was conducted to compare the effect of nebulized lignocaine with intravenous lignocaine on stress response to laryngoscopy and endotracheal intubation among the patients undergoing elective surgery under general anaesthesia. Mean pulse rate of subjects was 85.0±13.1 per minute, increased to 109.1±15.1 per min after two minutes of endotracheal intubation and was 98.8±14.9 per min at five minutes. Mean arterial blood pressure (MAP) of subjects was 94.2±7.8 mm of Hg, increased to 114.8±10.7 mm of Hg after two minutes of endotracheal intubation and was 98.7±11.7 mm of Hg at five minutes. The difference in mean arterial pressure among the three study groups was significant statistically at two minutes (p=0.00) as well as at five minutes (p=0.00). It is concluded that the hemodynamic instability after endotracheal intubation was lesser with nebulized lignocaine as compared to intravenous lignocaine.
Authors and Affiliations
Amar Nath Gupta, Ravi Anand, Ramanuj Singh
Keywords
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- EP ID EP449584
- DOI 10.26611/1015825
- Views 127
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