Comparative Study of Newer and Conventional Risk Factors of Coronary Artery Disease in Young Patients: A Case-Control Study from a Centre in Uttar Pradesh, India
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Aim: To analyze the young patients with coronary artery disease in relation to the levels of Apolipoprotein A-I and B, Lipoprotein (a), and hs-CRP and to study their relation with other conventional risk factors. Methods: We conducted a case-control study on 156 subjects who were younger than 45 years of age. All the subjects underwent a detailed clinical history and examinations followed by biochemical investigations underlining th risk factors of coronary artery disease (CAD). 78 of these subjects were confirmed cases of CAD and the rest were normal controls. Statistical analysis was done using unpaired t-test and chi-square test. A value of p <0.05 was considered significant. Result: The levels of Serum Apolipoprotein A-I were significantly low and the levels of Serum Apolipoprotein B and Serum Lipoprotein (a) were significantly elevated in young CAD patients. The hs-CRP levels were elevated but it did not show any significant correlation with the presence of CAD in young individuals. Conclusion: Apolipoprotein A-I, Apolipoprotein B and Lipoprotein (a) are significant risk markers for CAD in young.
Authors and Affiliations
Mastakim A Mazumder, Manzoor A Parry, Hamad Jeelani, Shahzad Alam
Keywords
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- EP ID EP533062
- DOI 10.21276/ijmrp.2018.4.6.022
- Views 88
- Downloads 0
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