Comparative Study of Oral Nifedipine and Intravenous Labetalol for Control of Blood Pressure in Severe Preeclampsia
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 3
Abstract
Background-Hypertensive disorders complicates 5-10 % of all pregnancies and is the third common cause of maternal mortality and morbidity next to haemorrhage and infections. Methods- This longitudinal interventional study was conducted in the department of Obstetrics and Gynaecology, P.B.M and Associated Group of Hospitals, attached to Sardar Patel Medical College, Bikaner from February 2017 to January 2018. Results- The mean age of women in Group A was 24.16±4.40 while in Group B it was 24.60±4.92. Both drugs were approximately similar efficacious in reduction of blood pressure. Mean time duration to achieve desired blood pressure was less in group B than in group A and it was statistically significant. The significant difference was observed between mean doses given in both groups to control blood pressure. Conclusion- The choice of antihypertensive agent in severe hypertension in pregnancy should depend on the clinician's experience, familiarity, drug availability and cost of the drugs. This study has shown that both Nifedipine and Labetalol fulfill the criteria required for an antihypertensive drug to treat severe hypertension in pregnancy with adequate efficacy and safety. Both the drugs are equally effective for the same.
Authors and Affiliations
Dr. Santosh Khajotia
Keywords
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