Comparative Study of Plain Bupivacaine and Bupivacaine with Clonidine for Caudal Epidural in Paediatric Patients

Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6

Abstract

Aims and Objectives: To compare perioperative haemodynamic changes and complications, the quality and duration of post operative analgesia, total number of rescue analgesic doses required and degree and duration of sedation post operatively in each group. Material and Method:70 children of ASA grade I or II aged 5-10 years, undergoing elective infraumbilical surgies were randomly allocated to group A(n=35)(0.25% plain bupivacaine 1 ml/kg+1 ml normal saline) and group B(n=35)(0.25% bupivacaine 1 ml/kg + clonidine 1mcg/kg in 1 ml normal saline). Post operative pain scores, duration of analgesia, total number of rescue analgesic doses required, haemodynamic changes, perioperative complications and degree and duration of sedation were recorded. Pain score was assessed using OPS score, Results: The mean duration of analgesia in postoperative period was more in group B(9.20 ±0.76) hours as compared to Group A (4.9 ± 1.23) hours ;P<0.05.The children in group B had lower pain scores as compared to group A which was statistically significant. 100% patients in group A required two or more than two doses of rescue analgesic whereas in group B 85% patients required single dose of rescue analgesic and 12% patients required two doses of rescue analgesic in first 12 hours post operatively. Mean sedation scores were higher in group B as compared to group A Conclusion: Addition of clonidine (1 mcg/kg) to bupicaine (0.25% 1 ml/kg) to caudal epidural block prolongs the duration of analgesia in paediatric patients

Authors and Affiliations

Dr Shweta Mehta

Keywords

Related Articles

Pulsatile Neck: A Rare Case Report

Common carotid artery aneurysms are rare but lethal whenever present. Early diagnosis and adequate treatment is required in order to prevent rupture or neurologic sequelae. We represent a rare case of asymptomatic pulsat...

Gastroprotective Effects of Gloriosa Superba Tubers against HCL/Ethanol Induced Gastric Mucosal Injury in Rats

The purpose of this study was to evaluate gastroprotective activity of Gloriosa superba tuber extract (GSTE) on HCL/Ethanol induced gastric ulcers. Gloriosa superba plant is used for treatment of various diseases. Diseas...

Platelet-Rich Fibrin – A Review of Its Impact in Endodontics

As with every aspect of science, Endodontics is in a perpetual quest for the best outcome. In Endodontic surgery, this entails a faster and predictable healing, of both soft tissue and hard tissue. One of the recently re...

A Comparison of Placement of Different Drug Regimen in Socket after lower third Molar Surgery: A Prospective Study

Background: Prevention of alveolar osteitis can be either pharmacological or non pharmacological. The aim of this study was to compare the effects of different regimens for the prevention of alveolar osteitis following m...

Study of Clinical Profile of Acute Febrile illness with Thrombocytopenia

Introduction- Febrile thrombocytopenia is usually a condition commonly caused by infection like Malaria, Dengue fever, Enteric fever and Septicemia. It is one of the commonest presenting problems in Hospital. It is neces...

Download PDF file
  • EP ID EP286122
  • DOI -
  • Views 77
  • Downloads 0

How To Cite

Dr Shweta Mehta (2017). Comparative Study of Plain Bupivacaine and Bupivacaine with Clonidine for Caudal Epidural in Paediatric Patients. Journal of Medical Science And clinical Research, 5(6), 23230-23236. https://europub.co.uk/articles/-A-286122