Comparative Study of Platelet Indices between Term, Preterm and Small for Gestational Age Newborns

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 11


Abstract: Hemostasis in neonate is a dynamic entity which evolves gradually throughout the fetal period and early infancy.Physiological status of newborn affects the hemostasis mechanism. To evaluate the number and morphological parameters of blood platelets in preterm,full term SGA newborns and to compare it with platelet indices of full term appropriate for gestational age neonates.Thiswas a prospective study, blood samples of 90 newborns were collected in K2EDTA tubes within 24h of birth and platelet indices such as platelet count, mean platelet volume, plateletcrit and platelet distribution width were estimated using Mindray Coulter BC3000plus autoanalyser.Data regarding the neonatal physiological status with respect to prematurity ,gestational age were collected .The statistical analysis were mean ,standard deviation ,one way ANOVA test was used to compare differences of hemostatic parameters between SGA ,prematurity ,full term AGA.Average platelet count of preterm(206 x 103 /μL) and SGA (202x103/μL) was low compared with term neonates(256x103/μL) with a P value <0.0001.Average plateletcrit was decreased in preterm (0.17%) and SGA (0.19%) as compared with term (0.22%) with a P value <0.0001. Average Mean platelet volume of preterm (8.4fL) & SGA (8.29fL)was higher compared to term neonates (8.13fL) with a P = 0.008.Average platelet distribution width was significantly increased in preterm(16.46) and SGA(16.19) when compared to term neonates (15.57) with a P = 0.002. Platelet indices may represent easy and early biomarker for identification of thromboembolic status in neonates andthus improves the neonatal outcome. Keywords:Term, preterm, SGA, newborns, platelet indices

Authors and Affiliations

Prof. Sathyavathi R Alva, Dr. Ashwini K. T, Dr. Navya B. N


Related Articles

A Study of Intestinal Obstruction and Factors Affecting Morbidity and Mortality Ankur Bhatnagar1,Prashant Shrivastava2*, Arjit Singh3, Tanmay Anand4

Abstract: The present study intends to enumerate various etiological factors of intestinal obstruction and to study various factors that affect the morbidity and mortality from intestinal obstruction. 120 patients of int...

Recent Management of Retinoblastoma- A Review Article

Abstract: Retinoblastoma is the commonest primary intraocular malignancy of childhood. Reported incidence varies from 1 in 15,000 to 1 in 18,000 live births. Early detection and treatment of retinoblastoma can not only s...

Fasting Blood Glucose Levels and Lipid Profile in Patients with Thyroid Dysfunction

The function of the thyroid gland is to keep the oxidative metabolism of body tissues at normal levels. The most important effect of thyroid hormones is to increase the metabolic rate and oxygen consumption of all tissue...

Laparoscopic Management of Advanced Un-ruptured Caesarean Scar Ectopic Pregnancy

Abstract: The implantation of conceptus within previous caesarean section scar is the rare site of ectopic pregnancy. Early diagnosis and treatment can avoid life threatening complications and save the uterus and future...

Solid Malignant Tumors of Infancy and Childhood: A Histopathological Study

In general, the features of malignancies in children differ biologically and histologically from those of adults with respect to incidence, type of tumor, underlying familial or genetic aberration and Tendency to regress...

Download PDF file
  • EP ID EP371650
  • DOI -
  • Views 15
  • Downloads 0

How To Cite

Prof. Sathyavathi R Alva, Dr. Ashwini K. T, Dr. Navya B. N (2016). Comparative Study of Platelet Indices between Term, Preterm and Small for Gestational Age Newborns. Scholars Journal of Applied Medical Sciences, 4(11), 3985-3989.