Comparative study of response to experimental cold pain in dysmenorrheic and nondysmenorrheic women
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 4
Abstract
Background: There has been keen research interest into the gender differences in tolerance of pain sensation. Dysmenorrheic pain is common among women of reproductive age group. Assessment of pain perception will result in better management of this chronic state. In this era of personalized medicine, optimizing analgesic treatment in patients with chronic pain is essential. Aims and Objectives: To compare levels of pain threshold and pain tolerance determined using cold pressor test in dysmenorrheic and nondysmenorrheic women during a single menstrual cycle in different phases. Materials and Methods: This is a comparative study done on 31 dysmenorrheic and nondysmenorrheic women between the ages of 18 and 22 years conducted in a tertiary care institution. We performed cold pressor test on 1st, 14th, and 21st day of menstrual cycle denoting the menstrual phase, late follicular phase, and luteal phase on the participants. Results: The levels of pain tolerance and pain threshold were significantly higher in dysmenorrheic women in comparison to nondysmenorrheic women. Conclusions: Higher thresholds may be supportive of a model of pain adaptation as dysmenorrheic women tend to compare cold pressor pain with internal menstrual pain. The knowledge of varying pain perception would benefit the gynecologists in dose adjustments of analgesics.
Authors and Affiliations
Vineetha K Ramdas Nayak, Shankarappa Chikkanna, Joshi Vidya, Mayanglambam Sangeeta Devi
Study of prescribing patterns of hypolipidemic agents in a tertiary care teaching hospital in North India
Background: Lipid-lowering agents are now the cornerstone of treatment used to reduce the risk of coronary events. Since there is wide variation in selection and use of these drugs, drug utilization studies help to evalu...
A cross-sectional study on the role of laughter therapy on regulation of blood pressure in Visakhapatnam population
Background: Laughter has positive effects on certain aspects of health and has a significant role in the management of cardiovascular health. Aims and Objectives: The aim and objective is to study the role of laughter th...
Comparative study of safety and efficacy of omeprazole, lansoprazole, and rabeprazole in triple therapy for eradication of Helicobacter pylori in peptic ulcer patients in Indian population
Background: Triple therapy which includes a proton pump inhibitor (PPI) along with two antimicrobials is routinely used for the eradication of Helicobacter pylori. Multiple regimens are reported using different combinati...
Arsenic trioxide-induced QT interval prolongation: A case report
QT prolongation refers to the prolonged QT interval in electrocardiography (ECG) which can even lead to life-threatening events such as ventricular arrhythmias, torsades de pointes, etc., several drugs can cause QT prolo...
Dynamics of the content of free amino acids in blood of patients during the long-term use of orthopedic dental metal prostheses
Background: The effect of materials for dental prostheses on the patient’s body remains one of the most relevant issues in orthopedic dentistry. The dentist, more often the orthopedist, has to deal with diseases arising...