Comparative study of risk factors and lipid profile pattern in ischemic and haemorrhagic stroke
Journal Title: Journal of Medical and Allied Sciences - Year 2016, Vol 6, Issue 1
Abstract
Stroke is a devastating and disabling cerebrovascular disease with significant amount of residual deficit leading on economic loss. Creating awareness on common risk factors will reduce the incidence of stroke. The study was conducted to compare the risk factors and lipid profile pattern in ischemic and hemorrhagic strokes. This was a descriptive retrospective cross sectional study carried on new onset acute stroke patients admitted to Osmania General Hospital, Telangana State. 100 patients (n=50 ischemic stroke (isch), n=50 hemorrhagic stroke (haem) were studied over a period of one year from May 2014 to April 2015. Data such as risk factors like hypertension, diabetes, smoking, alcohol, fasting lipid profile, CT or MRI brain were collected from medical records. A total of 100 patients were studied of whom 68 were males (isch n=32, haem n=36) and 32 were females (isch n=18, haem n=14). Patients with age <40 years were n=10; age between 41-59 years n=53 and age >60 years n=37. Risk factors included were hypertension n= 62 (isch n=29, haem n=33), diabetes n=22 (isch n=12, haem n=10), both diabetes and hypertension n=15; smoking n=41 (isch n=24, haem n=17) alcoholism n=38 (isch n=22, haem n=16) and >2 risk factors in n=46 (isch n=26, haem n=20). Dyslipidemia (LDL >130, TC>200, HDL<40) as per ATP III guidelines was present in n=69 (43 isch+26 haem) patients. Patients with high LDL were n=15 (9 isch, 6 haem), high total cholesterol was found in n=15 (10 isch, 5 haem), low HDL cholesterol in n=60 (isch n=35, haem n=25) with a p=0.0124. Present study concludes hypertension in 62 %, low HDL (< 40 mg/dl) in 60 %, smoking in 41% are the risk factors for both ischemic and haemorrhagic strokes which are modifiable risk factors. Low HDL cholesterol is more significant with a p=0.0124 which can be improved by exercise.
Authors and Affiliations
Ravala Siddeswari| Department of General Medicine, Osmania General Hospital, Afzalgunj, Hyderabad-500012, Telangana, India, Barla Suryanarayana| Department of General Medicine, Osmania General Hospital, Afzalgunj, Hyderabad-500012, Telangana, India, Budithi Sudarsi| Department of General Medicine, Osmania General Hospital, Afzalgunj, Hyderabad-500012, Telangana, India, Siddula Manohar| Department of General Medicine, Osmania General Hospital, Afzalgunj, Hyderabad-500012, Telangana, India, Nanyam Srinivasa Rao| Department of General Medicine, Osmania General Hospital, Afzalgunj, Hyderabad-500012, Telangana, India, Thatikala Abhilash| Department of General Medicine, Osmania General Hospital, Afzalgunj, Hyderabad-500012, Telangana, India
Keywords
Related Articles
- EP ID EP12737
- DOI 10.5455/jmas.210760
- Views 374
- Downloads 22
Cardiovascular diseases: Traditional and nontraditional risk factors
Cardiovascular disease (CVD) is responsible for more number of deaths worldwide. The muscles and vessels of heart and blood transporting roads become vulnerable portion in most of the CVD. The role of hypertension and...
Medicine is ever changing, so also medical practitioners
Pattern of dyslipidemia in ischemic stroke
The study aimed to assess dyslipidemia pattern including role of non HDL cholesterol (non HDLc) in ischemic strokes. A retrospective descriptive was conducted on 80 patients who were admitted to Osmania General Hospita...
Method development and validation of paracetamol drug by RP-HPLC
A simple and reproducible method was developed for paracetamol by Reverse Phase High Performance Liquid Chromatography (RP-HPLC). Paracetamol was separated on C18 column [4.6x250mm, particle size 5μm], using ortho ph...
Periocular anthropometric study among adult Bangladeshi Buddhist Chakma females
The dimensions of the human body are affected by geographical, racial, ethnic, gender and age factors. So, a normative data of periocular measurements based on above factors are indispensable to identify any ocular pat...