Comparative Study of Serum PRL, LH, FSH in Overt and Subclinical Hypothyroid Females in Reproductive Age Group
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Hypothyroidism is associated with an increase in the levels of thyroid releasing hormone (TRH) which in turn stimulates secretion of thyroid stimulating hormone (TSH) and prolactin (PRL). PRL inhibits the synthesis and secretion of gonadotropins (FSH & LH). Abnormal menstrual patterns are commonly observed in overt hypothyroidism.1 Studies considering an association between overt hypothyroidism and female reproductive hormones are not adequate particularly in eastern India. Therefore, present study is aimed to evaluate the relationship between overt and subclinical hypothyroidism and female reproductive hormones. Subjects were randomly selected having high TSH level.They were categorized into subclinical and overt hypothyroid. Results were analysed by using Graph pad prism 5, comparison was done using independent group t test and correlation was determined by Pearson’s correlation coefficient. Result showed that with overt hypothyroidism PRL increased and FSH & LH decreased significantly whereas in subclinical hypothyroidism PRL increased but FSH and LH are not significantly decreased. Most of the patients presented with oligomenorrhea .
Authors and Affiliations
Srila Ghosh Chowdhury, Amiya Kumar Sarkar
Keywords
Related Articles
- EP ID EP441057
- DOI 10.9790/0853-1801126568.
- Views 80
- Downloads 0
A Comparative Study of Halothane versus Sevoflurane for Induction of Anaesthesia and Tracheal Intubation in Children
Inhalational anaesthesia is the most commonly employed technique in paediatric age group since it is associated with rapid induction and emergence. Halothane has been very popular as it is non-irritant and well tolerated...
Sites of Infections and choice of antimicrobial drugs in acute leukemia in Indian Children
In this study children with acute leukemia were evaluated for the incidence and sites of infection, correlation with absolute neutrophil count, causative organisms and to standardize the initial empirical anti microbial...
Color Doppler Evaluation of Carotid Arteries in Stroke Patients: A Study Conducted in A rural Tertiary Care Medical College Hospital in South india.
Aims and Objectives: Cerebral ischemic stroke is life-threatening and debilitating neurological disease, it is the third leading cause of death in the world. Studies have shown that there is a close relationship between...
Analysing Two Bulky Eggs In An Eagles Nest: Analysis Of Unenhanced & Contrast Enhanced Computed Tomography Study Of Adnexa To Reduce Radiation Exposure In Adnexal Pathologies.
The primary goal of imaging study is to detect an abnormality, then characterize whether malignant or benign.Various modalities have been established,each having their own pros and cons.When it comes to gynecological ima...
Clinico-Epidemiological Profile of Elderly Patients with NonAlcoholic Fatty Liver Disease
Introduction:Most patients of Non-alcoholic fatty liver disease (NAFLD) are in the age group of 40 to 50 years, which is also associated with more severe liver fibrosis and higher mortality. In this study we aim to under...