COMPARATIVE STUDY OF WOODFORDIA FRUTICOSA AND CATHARANTHUS ROSEUS LEAVES FOR PHYTOCHEMICAL, ANTIOXIDANT AND ANTIBACTERIAL PROPERTIES
Journal Title: International Journal of Medicine and Pharmaceutical Sciences (IJMPS) - Year 2017, Vol 7, Issue 1
Abstract
In present study various solvent extracts of leaves have been used for comparative study of Woodfordia fruticosa and Catharanthus roseusn for their natural bioactive compound, antioxidant properties and antibacterial properties and were confirmed by TLC. Here Chloroform extracts was found to be effective solvents for alkaloid and terpenoid, Methanol was for flavonoid and tannin and aqueous extract was found to be effective solvent for cardiac glycoside and saponin. The results also revealed that Woodfordia fruticosa leaves extracts has higher percentage of tannin (1.496%) as compare to Catharanthus roseus with value (0.693%) whereas antioxidant property of Woodfordia fruticosa was poor (1.1 µmole/ml glutathione) in comparison with Catharanthus roseus (25.09 µmole/ml glutathione). Antimicrobial assay showed that methanolic extracts of Woodfordia fruticosa in comparison with Catharanthus roseus were more effective than other solvent extracts with (14mm/9mm, 19mm/4mm, 17mm/8 mm, 11mm/9mm) zone of inhibition against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa respectively. This comparative results obtained in the present study would be useful option for future drugs discoveries to cure various diseases.
Authors and Affiliations
VIKRANT KUMAR SAHU, SHOWKAT AHMAD
Keywords
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