Comparative Study On Antimicrobial Susceptibility In Clinical Isolates At A Tertiary Care Teaching Hospital In South India
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 6
Abstract
: Antimicrobial resistance is an issue of great significance for public health at global level. The purpose of study is to determine the susceptibility patterns of microrganisms to antibiotics and the prevalence of antibiotic resistance among common pathogens in a tertiary care teaching hospital. The study was conducted in a 1000 bedded multispecialty hospital in South India. The study was carried out in three phases as retrospective, prospective and comparative study. The major organism isolated was Klebsiella followed by Staphylococcus. E.coli and Klebsiella were found to be more sensitive to Amikacin. Specimen in which Klebsiella, Pseudomonas and Streptococcus were found to be more was in sputum. E.coli and Proteus were present more in urine. Staphylococcus was seen more in blood and sputum. Enterococci and Salmonella were majorly seen in blood.The sensitivity of E.coli to Gentamicin has decreased from 50.5 % to 30%. Klebseilla to Amikacin has decreased from 84.85% to 70.6%. Pseudomonas to Ofloxacin has decreased from 62.9% to 25%. Proteus to Ofloxacin 45.4% to 25% and Streptococcus to Amikacin from 53.9% to 40%. As there is increasing international concern regarding the escalating antibiotic resistance, periodical study on the control of antibiotic resistance in necessary. This can be achieved only when proper sensitivity pattern data are available. The pharmacist role in advising prescribers on antibiotic prescribing issues gained more impotence in adhering to rational drug therapy and complete patient care. The study revealed that clinical pharmacists play an important role in promoting optimal antibiotic prescribing practice among physicians, during their routine daily visit to wards.
Authors and Affiliations
s. Sriram, akshaya . N, sumiya. M. Varghese, vaishna . M. S, vijayshrivel . V, prasanna Rm
Keywords
Related Articles
- EP ID EP415713
- DOI 10.9790/3008-1306011224.
- Views 64
- Downloads 0
Efficacy and Safety of Herbal Formulations Used For Management of Hiv/Aids In Mombasa County
Background: Traditional medicines are not understood globally and hence are not fully exploited. Pwani herbs clinic in Mombasa dispenses herbal medicines to manage HIV and AIDS. There was need to subject these herbs to f...
Knowledge, Attitude and Practice Concerning Using Cosmetic among Females at Najran University, Saudi Arabia
This is a cross sectional descriptive study that aims to assess women’s knowledge, attitude and practice towards using cosmetics as well as their behaviour towards cosmetic purchase and its effect on personal budget.The...
Synergism effect of rosemary essential oil and some antibiotic against Escherichia coli isolated from clinical samples
Urinary tract infections (UTI) are among the most common infections in humans worldwide, E. coli strains in particular are responsible for 80% of the UTI cases. Therefore, the study aimed to investigate the antimicrobial...
Anti –Mullerian Hormone is a new Marker for Ovarian function in females with polycystic ovary syndrome
Anti-Mullerian Hormone (AMH) is a member of the transforming growth and differentiation factors in the ovary, AMH has an inhibitory effect on primordial follicle recruitment as well as on the responsiveness of growth fol...
Extraction and purification of ßeta-galactosidase from a Local Almond seeds(Prunusamygdalus)
ßeta-galactosidaseenzyme is greatly dispersed in plant tissues and it’s known to be implicated in hydrolyzing terminal non reducingß.D.Galactosyl residues from polysaccharides . This study involved the selection of the b...