Comparative Study On Antimicrobial Susceptibility In Clinical Isolates At A Tertiary Care Teaching Hospital In South India
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 6
Abstract
: Antimicrobial resistance is an issue of great significance for public health at global level. The purpose of study is to determine the susceptibility patterns of microrganisms to antibiotics and the prevalence of antibiotic resistance among common pathogens in a tertiary care teaching hospital. The study was conducted in a 1000 bedded multispecialty hospital in South India. The study was carried out in three phases as retrospective, prospective and comparative study. The major organism isolated was Klebsiella followed by Staphylococcus. E.coli and Klebsiella were found to be more sensitive to Amikacin. Specimen in which Klebsiella, Pseudomonas and Streptococcus were found to be more was in sputum. E.coli and Proteus were present more in urine. Staphylococcus was seen more in blood and sputum. Enterococci and Salmonella were majorly seen in blood.The sensitivity of E.coli to Gentamicin has decreased from 50.5 % to 30%. Klebseilla to Amikacin has decreased from 84.85% to 70.6%. Pseudomonas to Ofloxacin has decreased from 62.9% to 25%. Proteus to Ofloxacin 45.4% to 25% and Streptococcus to Amikacin from 53.9% to 40%. As there is increasing international concern regarding the escalating antibiotic resistance, periodical study on the control of antibiotic resistance in necessary. This can be achieved only when proper sensitivity pattern data are available. The pharmacist role in advising prescribers on antibiotic prescribing issues gained more impotence in adhering to rational drug therapy and complete patient care. The study revealed that clinical pharmacists play an important role in promoting optimal antibiotic prescribing practice among physicians, during their routine daily visit to wards.
Authors and Affiliations
s. Sriram, akshaya . N, sumiya. M. Varghese, vaishna . M. S, vijayshrivel . V, prasanna Rm
Keywords
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- EP ID EP415713
- DOI 10.9790/3008-1306011224.
- Views 73
- Downloads 0
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