Comparative Study That Evaluates the Effectiveness of Intradermotherapy with 0.5% Minoxidil Versus Topical Application of 5% Monoxidil Solution in the Treatment of Androgenetic Alopecia
Journal Title: Journal of Dermatology Research - Year 2025, Vol 6, Issue 1
Abstract
Introduction: Androgenetic alopecia is the most common cause of hair loss, progressively affecting both men and women and causing great impact on quality of life. Among many possible treatments, intradermotherapy is a promising and controversial procedure, with few studies in the literature so far. Objectives: Comparatively evaluate the efficacy of intradermotherapy with a 5% minoxidil solution in patients with androgenetic alopecia. Methods: Patients were randomly divided into two groups. Group 1, with 13 participants, went through 10 sessions of intradermotherapy with 7 day intervals between each one. Group 2, with 11 participants, applied 1 ml of a topical minoxidil 5% solution on dry scalp twice a day throughout this study. All patients were evaluated with clinical and trichoscopic pictures taken before and after 12 weeks of treatment. Results: Most patients in both groups perceived improved capillary density and thickness of hair strands, and reduced hair loss, without statistical difference between group 1 and 2. Trichoscopic evaluation performed by specialists did not find statistical difference between the groups. Conclusion: The results of intradermotherapy with minoxidil are similar to the results of topical application of the same substance.
Authors and Affiliations
Priscila Regina Orso Rebellato1*, Carolina Labigalini Sampaio2, Giovana Liz Marioto de Campos1, Adriane Costa3, Andrea Buosi Fabre4, Juliano Vilaverde Schmitt5
Keywords
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- EP ID EP758355
- DOI https://doi.org/10.46889/JDR.2025.6103
- Views 39
- Downloads 0
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