Comparative Study to Analyse the Lymphocytic Count In Pre-Menopausal Women with Iron Deficiency Anemia
Journal Title: Harsukh Educational Charitable Society International Journal of Community Health and Medical Research - Year 2018, Vol 4, Issue 3
Abstract
Background: Iron is vital for all living organisms because it is essential for multiple metabolic processes, including DNA synthesis and oxygen and electron transport. Iron deficiency is a main nutritional deficiency disorder affecting large fractions of the world population and is a common cause of anemia. Iron deficiency anemia (IDA) is characterized by a defect in hemoglobin synthesis, resulting in red blood cells that are abnormally small (microcytic) and contain a decreased amount of hemoglobin (hypochromic). Aim of the study: To evaluate the lymphocytic count in pre-menopausal women with iron deficiency anemia. Materials and methods: The study was conducted in the Department of General Pathology of the medical institution. For the study, we selected 50 pre-menopausal women between the age group of 18-35 years. It was made sure that the subjects selected for the study are anemic having hemoglobin less than 10 g/dL. For the control group, 50 pre-menopausal women with normal hemoglobin level were included. The patients with thalassemia, leukemia or any other chronic and autoimmune disease were excluded from the study. Laboratory evaluation of each subject was done. Results: The mean age of the patients in study group was 26.12 years and in control group was 25.22 years. There were 50 subjects in each group. The mean CD3+, CD4+, CD8+, and CD19+ lymphocyte counts were 1.56, 0.79, 0.55, and 0.39 X109/L, respectively, in study group, and 1.89, 0.49, 0.71, and 0.29 X 109/L, respectively, for the control group. The absolute T lymphocytes (CD3+) and subpopulations (CD4+, CD8+) in the iron-deficient group were significantly lower than in the control group. On comparing the results, menopausal women with iron deficiency anemia have significant change in the total lymphocyte count. Due to decreased lymphocyte count in pre-menopausal women with IDA, these patients may be more prone to infection.
Authors and Affiliations
Dr. Meera Mathur, Dr. Anshu Mishra, Neha Kumari
Keywords
Related Articles
- EP ID EP492484
- DOI -
- Views 101
- Downloads 0
Keratocystic Odontogenic Tumor of the Mandible- A Case Report
Keratocystic odontogenic tumor is considered to be a benign cystic neoplasia of jaw bone with a higher rate of recurrence. It is noted to be third most common odontogenic cyst after radicular and dentigerous cyst. It has...
Assessment Of Risk Factors In Development Of Cutaneous Melanoma- A Clinical Study
Background: Cutaneous melanoma (CM) is one of the commonest occurring skin cancers. It is affecting large amount of world population. The present study was conducted to determine the risk factors associated with cutaneou...
The prevalence of oral mucosal lesions in the pediatric populationvisiting a dental school of Uttar Pradesh: A cross sectional study
Background-Lesions of the oral mucosa are located in the soft tissue of the oral cavity. Most of the studies Abstract describe the prevalence of oral mucosal lesions mainly in an adult population and only few reports hav...
Analysis Of Cases Of Chickenpox In Children- A Clinical Study
Background: Chickenpox is the primary infection caused by the varicella-zoster virus. It is an acute, highly infectious disease most commonly seen in children under 10 years old. The present study was conducted to assess...
Assessment of variation of scapula- A Morphological study
Background: The scapula is a flat triangular bone situated posteriorly overlying the second to seventh ribs on both the side. The present study was conducted to determine the morphological type of scapulae. Materials & M...