COMPARATIVE STUDY TO EVALUATE LIPID-LOWERING EFFECT OF FENOFIBRATE VERSUS ATORVASTATIN IN PATIENTS WITH HYPERTRIGLYCERIDAEMIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 26
Abstract
BACKGROUND Dyslipidaemia is a widely established risk factor for coronary artery disease. As Asians differ in pattern of various lipid abnormalities than non-Asians, this study was undertaken to compare efficacy of commonly administrated drugs, atorvastatin and fenofibrate. MATERIALS AND METHODS The present study was carried out in 100 diagnosed cases of hypertriglyceridaemia divided into two groups, A and B. The mean, standard deviation, standard error of mean and t value were calculated following 12 weeks of therapy of atorvastatin 10 mg in group A and micronized fenofibrate in group B. RESULTS Our study showed that fenofibrate is more efficacious in reducing the levels of triglycerides and rising level of HDL cholesterol, while atorvastatin is more efficacious in reducing LDL cholesterol. CONCLUSION Micronized fenofibrate has more efficiency in reducing triglycerides and raising HDL. Atorvastatin is more efficacious in reducing LDL levels.
Authors and Affiliations
Niteesh Shanbag, Vijay Naik, Bharathraj M. Y
Keywords
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- EP ID EP217147
- DOI 10.18410/jebmh/2017/301
- Views 97
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