Comparing the Effect of Dextrose and Oxytocin to Reduce Postpartum Haemorrhage: Randomised Controlled Trial
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 7
Abstract
ABSTRACT Introduction: Post-partum haemorrhage is a leading cause of maternal mortality and morbidity worldwide. There are different management procedures adopted for the treatment of post-partum haemorrhage. Aim: To evaluate the efficacy of dextrose in Post-partum Haemorrhage (PPH) and compare it with Oxytocin (a conventional method). Materials and Methods: A two-arm randomised controlled trial was conducted among 120 pregnant women admitted to the delivery room of the Obstetric and Gynaecological Unit of a Teaching Hospital. Participants were randomised to receive either 20 unit of oxytocin in 1000 mL ringer lactate solution (routine administration, control group) or 200 mL of 10% dextrose solution (intervention group). The primary outcome measured in this study was amount of blood loss. The outcome was assessed at 1 hour and 2 hours. Data were analysed using SPSS version 22.0, chi-square and student’s t-tests. Authors used expected maximisation to handle missing data to enable an intention-to-treat analysis. Results: At baseline, the groups were homogeneous in regards to socio-demographic variables. The average blood loss was significantly lower in the intervention group (dextrose 10%) compared to the control group (oxytocin) (p<0.05). Conclusion: Administering of dextrose 10% to pregnant women at the third stage of labour was associated with lower post-partum haemorrhage than oxytocin.
Authors and Affiliations
Zainab Suhrabi, Malihe Akbari, Hamid Taghinejad, Golnaz Azami
Keywords
Related Articles
- EP ID EP606710
- DOI 10.7860/JCDR/2019/35479.12987
- Views 118
- Downloads 0
Non Lactational Breast Abscess due to Actinomyces odontolyticus: First Case Report from Asia
ABSTRACT Actinomycosis is a chronic infection caused by the aerotolerant anaerobe, Actinomyces spp., characterised by the formation of abscess, draining sinuses and tissue fibrosis. Primary actinomycosis of the breast is...
Bronchogenic Cyst over Sternum–An Unusual Location
Abstract Bronchogenic cyst is congenital anomaly arising from the abnormal budding of the tracheobronchial tree during foregut maturation. The cyst is most commonly located in mediastinum and intraparenchymal region. Su...
Incontinence Impact Questionnaire (IIQ-7) and Urogenital Distress Inventory (UDI-6): Translation and Psychometric Validation of the Iranian Version
ABSTRACT Introduction: Urinary incontinence is a common health, physical, and social problem in the world. There is an urgent need of effective questionnaires for its evaluation in Iranian women. Aim: The present study a...
A Prospective Analysis of Drug Interactions in Patients of Intensive Cardiac Care Unit
Introduction: Drug-Drug Interaction (DDI) is a serious concern in cardiac patients due to polypharmacy. Aim: The present study was aimed to identify the potential DDI among hospitalized cardiac patients and evaluate the...
Change in Bone Mineral Density and Role of Vitamin D and Calcium Supplementation During Treatment of First Episode Nephrotic Syndrome
Introduction: Nephrotic Syndrome (NS) is one of the common illnesses in childhood. Oral glucocorticoids are mainstay of treatment, which are known to cause various short term and long term adverse effects including osteo...