Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment

Journal Title: Translational Research in Urology - Year 2021, Vol 3, Issue 2

Abstract

Introduction: For erectile dysfunction (ED) treatment, Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and increase the blood inflow to the penis. In the current study, we evaluated the vacuum constrictive device (VCD) and intracavernosal injection (ICI) of papaverine for the treatment of ED. Methods: A total number of 80 erectile dysfunctions (ED) were divided into 4 groups of 20 couples. The first group was treated with Papaverine who had a virgin wife (a). The second group was unconsummated marriage couples who were treated with vacuums (b). The third group was the couples with experience of sexual intercourse who had been treated with Papaverine injection (c). The fourth group was the couples with experience of sexual intercourse that were treated with a vacuum device (d). Results: After 4 months of treatment, all patients were able to have sex. In the unconsummated couples group treated with papaverine and consummated couples treated with papaverine, all of the indicators of the erectile function were significantly increased compared to pre-treatment (p-value<0.05). There were no significant differences between the two methods in terms of other complications such as ecchymosis, blisters, headache, cutaneous rash, and vaso-vascular shock (p-value>0.05). Conclusions: This study showed that in patients with erectile dysfunction who are having virgin spouses and who are not responding to the first line of oral medication 5-inhibitors phosphodiesterase can be an excellent candidate for ICI of vasoactive drugs therapy.

Authors and Affiliations

Amir Ghasemlouei; Feraidoon Khayyamfar; Seyed Kazem Forootan; Amir Mahdi Khayyamfar; Masood Vahdani

Keywords

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  • EP ID EP704083
  • DOI 10.22034/TRU.2021.292902.1070
  • Views 82
  • Downloads 0

How To Cite

Amir Ghasemlouei; Feraidoon Khayyamfar; Seyed Kazem Forootan; Amir Mahdi Khayyamfar; Masood Vahdani (2021). Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment. Translational Research in Urology, 3(2), -. https://europub.co.uk/articles/-A-704083