COMPARING THE EFFICACY AND TOLERABILITY OF CARBAMAZEPINE AND OXCARBAZEPINE AS A MONOTHERAPY OF TRIGEMINAL NEURALGIA
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 11
Abstract
Trigeminal neuralgia is a condition characterized by recurrent short paroxysms of electrical shock-like pain with sudden onset affecting distribution of trigeminal nerve divisions in one side of face (Society, 2013). Trigeminal neuralgia is uncommon condition with estimated incidence of 40-130 cases per million per year (MacDonald et al., 2000, Katusic et al., 1991). It is more common in females than males and the incidence increases in older age, other risk factors include hypertension and migraine (Katusic et al., 1990, Maarbjerg et al., 2014, Pan et al., 2011, Lin et al., 2016). Clinically, light pressure or touch to the triggering zone, usually associated with face washing or tooth brushing, may trigger the pain episodes. Trigeminal neuralgia is classified into two types according to the etiology, the classical type caused by idiopathic lesions or vascular compression; and painful neuropathy that predisposed by herpes infection, multiple sclerosis, trauma and drugs therapy (Society, 2013). Pain of trigeminal neuralgia can be confused with dental pain especially in the phase of pre-trigeminal neuralgia characterized by atypical clinical picture (Fromm et al., 1990). Thus, the International Classification of Headache Disorders (ICHD) stated diagnostic criteria for classical trigeminal neuralgia including frequency of pain attacks, anatomical distribution, intensity and duration of pain attacks (Society, 2013).
Authors and Affiliations
Dr. Abdurlahman Abdurlahman
Keywords
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